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A kunitz-type protease inhibitor bikunin disrupts ligand-induced oligomerization of receptors for transforming growth factor (TGF)-beta and subsequently suppresses TGF-beta signalings.
Yagyu T, Kobayashi H, Wakahara K, Matsuzaki H, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Yagyu T, et al. Among authors: kurita n. FEBS Lett. 2004 Oct 22;576(3):408-16. doi: 10.1016/j.febslet.2004.09.048. FEBS Lett. 2004. PMID: 15498571 Free article.
Thalidomide inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endometriotic stromal cells, possibly through suppression of nuclear factor-kappaB activation.
Yagyu T, Kobayashi H, Matsuzaki H, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Yagyu T, et al. Among authors: kurita n. J Clin Endocrinol Metab. 2005 May;90(5):3017-21. doi: 10.1210/jc.2004-1946. Epub 2005 Feb 1. J Clin Endocrinol Metab. 2005. PMID: 15687330
Suppression of urokinase expression and invasion by a soybean Kunitz trypsin inhibitor are mediated through inhibition of Src-dependent signaling pathways.
Inagaki K, Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Kondo T, Kurita N, Kitanaka T, Yamada Y, Sakamoto Y, Suzuki M, Kanayama N, Terao T. Inagaki K, et al. Among authors: kurita n. J Biol Chem. 2005 Sep 9;280(36):31428-37. doi: 10.1074/jbc.M501406200. Epub 2005 Jul 7. J Biol Chem. 2005. PMID: 16002410 Free article.
Enhanced spontaneous metastasis in bikunin-deficient mice.
Yagyu T, Kobayashi H, Matsuzaki H, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K. Yagyu T, et al. Among authors: kurita n. Int J Cancer. 2006 May 1;118(9):2322-8. doi: 10.1002/ijc.21293. Int J Cancer. 2006. PMID: 16331631 Free article.
Plasma bikunin as a favorable prognostic factor in ovarian cancer.
Matsuzaki H, Kobayashi H, Yagyu T, Wakahara K, Kondo T, Kurita N, Sekino H, Inagaki K, Suzuki M, Kanayama N, Terao T. Matsuzaki H, et al. Among authors: kurita n. J Clin Oncol. 2005 Mar 1;23(7):1463-72. doi: 10.1200/JCO.2005.03.010. J Clin Oncol. 2005. PMID: 15735122
473 results