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Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V, Fan H, Abruzzo G, Flattery A, Gill C, Chrebet G, Parent SA, Kurtz M, Teppler H, Douglas CM, Perlin DS. Park S, et al. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73. doi: 10.1128/AAC.49.8.3264-3273.2005. Antimicrob Agents Chemother. 2005. PMID: 16048935 Free PMC article. Clinical Trial.
Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors.
Onishi J, Meinz M, Thompson J, Curotto J, Dreikorn S, Rosenbach M, Douglas C, Abruzzo G, Flattery A, Kong L, Cabello A, Vicente F, Pelaez F, Diez MT, Martin I, Bills G, Giacobbe R, Dombrowski A, Schwartz R, Morris S, Harris G, Tsipouras A, Wilson K, Kurtz MB. Onishi J, et al. Among authors: kurtz mb. Antimicrob Agents Chemother. 2000 Feb;44(2):368-77. doi: 10.1128/AAC.44.2.368-377.2000. Antimicrob Agents Chemother. 2000. PMID: 10639364 Free PMC article.
66 results