Kusano K - Search Results

1

Importance of a proline-rich sequence in the amino-terminal region for correct folding of mitochondrial and soluble microbial p450s.

Kusano K, Kagawa N, Sakaguchi M, Omura T, Waterman MR. Kusano K, et al. J Biochem. 2001 Feb;129(2):271-7. doi: 10.1093/oxfordjournals.jbchem.a002854. J Biochem. 2001. PMID: 11173529 Free article.

All microsomal P450s have a proline-rich sequence (PR) in the amino-terminal region that is needed for proper folding [Kusano, K., Sakaguchi, M., Kagawa, N., Waterman, M.R. and Omura, T. (2001) J. ...

All microsomal P450s have a proline-rich sequence (PR) in the amino-terminal region that is needed for proper folding [Kusano, K …

2

Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli.

Kusano K, Waterman MR, Sakaguchi M, Omura T, Kagawa N. Kusano K, et al. Arch Biochem Biophys. 1999 Jul 1;367(1):129-36. doi: 10.1006/abbi.1999.1248. Arch Biochem Biophys. 1999. PMID: 10375408

3

Microsomal p450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure.

Kusano K, Sakaguchi M, Kagawa N, Waterman MR, Omura T. Kusano K, et al. J Biochem. 2001 Feb;129(2):259-69. doi: 10.1093/oxfordjournals.jbchem.a002853. J Biochem. 2001. PMID: 11173528 Free article.

4

Expression of human aromatase (CYP19) in Escherichia coli by N-terminal replacement and induction of cold stress response.

Kagawa N, Cao Q, Kusano K. Kagawa N, et al. Among authors: kusano k. Steroids. 2003 Feb;68(2):205-9. doi: 10.1016/s0039-128x(02)00168-x. Steroids. 2003. PMID: 12606012

5

Inoculation of human tumor cells alters the basal expression but not the inducibility of cytochrome P450 enzymes in tumor-bearing mouse liver.

Sugawara M, Okamoto K, Kadowaki T, Kusano K, Fukamizu A, Yoshimura T. Sugawara M, et al. Among authors: kusano k. Drug Metab Dispos. 2009 Nov;37(11):2244-54. doi: 10.1124/dmd.109.028571. Epub 2009 Aug 10. Drug Metab Dispos. 2009. PMID: 19666990

6

Expressions of cytochrome P450, UDP-glucuronosyltranferase, and transporter genes in monolayer carcinoma cells change in subcutaneous tumors grown as xenografts in immunodeficient nude mice.

Sugawara M, Okamoto K, Kadowaki T, Kusano K, Fukamizu A, Yoshimura T. Sugawara M, et al. Among authors: kusano k. Drug Metab Dispos. 2010 Mar;38(3):526-33. doi: 10.1124/dmd.109.030668. Epub 2009 Dec 9. Drug Metab Dispos. 2010. PMID: 20007293

7

Purification and characterization of rhesus monkey liver amido hydrolases and their roles in the metabolic polymorphism for E6123, a platelet-activating factor receptor antagonist.

Kusano K, Seko T, Tanaka S, Shikata Y, Ando T, Ida S, Hosokawa M, Satoh T, Yuzuriha T, Horie T. Kusano K, et al. Drug Metab Dispos. 1996 Nov;24(11):1186-91. Drug Metab Dispos. 1996. PMID: 8937851

8

A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.

Ueda R, Iketaki H, Nagata K, Kimura S, Gonzalez FJ, Kusano K, Yoshimura T, Yamazoe Y. Ueda R, et al. Among authors: kusano k. Mol Pharmacol. 2006 Jun;69(6):1924-30. doi: 10.1124/mol.105.021220. Epub 2006 Feb 27. Mol Pharmacol. 2006. PMID: 16505155

9

Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements.

Yoshinari K, Ueda R, Kusano K, Yoshimura T, Nagata K, Yamazoe Y. Yoshinari K, et al. Among authors: kusano k. Biochem Pharmacol. 2008 Jul 1;76(1):139-45. doi: 10.1016/j.bcp.2008.04.005. Epub 2008 Apr 16. Biochem Pharmacol. 2008. PMID: 18502397

10

Unique metabolic pathway of [(14)C]lenvatinib after oral administration to male cynomolgus monkey.

Inoue K, Asai N, Mizuo H, Fukuda K, Kusano K, Yoshimura T. Inoue K, et al. Among authors: kusano k. Drug Metab Dispos. 2012 Apr;40(4):662-70. doi: 10.1124/dmd.111.043281. Epub 2011 Dec 29. Drug Metab Dispos. 2012. PMID: 22207053

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