Kutateladze TG - Search Results

1

A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.

Burgoyne AM, Vann KR, Joshi S, Morales GA, Vega FM, Singh A, Pal D, Merati AB, Kutateladze TG, Durden DL. Burgoyne AM, et al. Among authors: kutateladze tg. Cell Discov. 2020 Jul 28;6(1):49. doi: 10.1038/s41421-020-0181-z. eCollection 2020. Cell Discov. 2020. PMID: 32793389 Free PMC article. No abstract available.

2

Epigenetic countermarks in mitotic chromosome condensation.

van Wely KH, Mora Gallardo C, Vann KR, Kutateladze TG. van Wely KH, et al. Among authors: kutateladze tg. Nucleus. 2017 Mar 4;8(2):144-149. doi: 10.1080/19491034.2016.1276144. Epub 2017 Jan 3. Nucleus. 2017. PMID: 28045584 Free PMC article. Review.

3

Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis.

Andrews FH, Singh AR, Joshi S, Smith CA, Morales GA, Garlich JR, Durden DL, Kutateladze TG. Andrews FH, et al. Among authors: kutateladze tg. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1072-E1080. doi: 10.1073/pnas.1613091114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137841 Free PMC article.

4

Histone H3 Dual Ubiquitylation Mediates Maintenance DNA Methylation.

Vann KR, Kutateladze TG. Vann KR, et al. Among authors: kutateladze tg. Mol Cell. 2017 Oct 19;68(2):261-262. doi: 10.1016/j.molcel.2017.10.007. Mol Cell. 2017. PMID: 29053953 Free article.

5

Yaf9 subunit of the NuA4 and SWR1 complexes targets histone H3K27ac through its YEATS domain.

Klein BJ, Ahmad S, Vann KR, Andrews FH, Mayo ZA, Bourriquen G, Bridgers JB, Zhang J, Strahl BD, Côté J, Kutateladze TG. Klein BJ, et al. Among authors: kutateladze tg. Nucleic Acids Res. 2018 Jan 9;46(1):421-430. doi: 10.1093/nar/gkx1151. Nucleic Acids Res. 2018. PMID: 29145630 Free PMC article.

6

Architecture of PRC2 Holo Complexes.

Vann KR, Kutateladze TG. Vann KR, et al. Among authors: kutateladze tg. Trends Biochem Sci. 2018 Jul;43(7):487-489. doi: 10.1016/j.tibs.2018.04.009. Epub 2018 May 3. Trends Biochem Sci. 2018. PMID: 29731341 Free PMC article.

7

Structural insights into the π-π-π stacking mechanism and DNA-binding activity of the YEATS domain.

Klein BJ, Vann KR, Andrews FH, Wang WW, Zhang J, Zhang Y, Beloglazkina AA, Mi W, Li Y, Li H, Shi X, Kutateladze AG, Strahl BD, Liu WR, Kutateladze TG. Klein BJ, et al. Among authors: kutateladze tg, kutateladze ag. Nat Commun. 2018 Nov 1;9(1):4574. doi: 10.1038/s41467-018-07072-6. Nat Commun. 2018. PMID: 30385749 Free PMC article.

8

MORC3 Is a Target of the Influenza A Viral Protein NS1.

Zhang Y, Ahn J, Green KJ, Vann KR, Black J, Brooke CB, Kutateladze TG. Zhang Y, et al. Among authors: kutateladze tg. Structure. 2019 Jun 4;27(6):1029-1033.e3. doi: 10.1016/j.str.2019.03.015. Epub 2019 Apr 18. Structure. 2019. PMID: 31006586 Free article.

9

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.

Zhang Y, Guo Y, Gough SM, Zhang J, Vann KR, Li K, Cai L, Shi X, Aplan PD, Wang GG, Kutateladze TG. Zhang Y, et al. Among authors: kutateladze tg. Nat Commun. 2020 Jul 3;11(1):3339. doi: 10.1038/s41467-020-17098-4. Nat Commun. 2020. PMID: 32620764 Free PMC article.

10

Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.

Vann KR, Pal D, Morales GA, Burgoyne AM, Durden DL, Kutateladze TG. Vann KR, et al. Among authors: kutateladze tg. Sci Rep. 2020 Jul 21;10(1):12027. doi: 10.1038/s41598-020-68964-6. Sci Rep. 2020. PMID: 32694708 Free PMC article.

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