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SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release.
Junqueira C, Crespo Â, Ranjbar S, Lewandrowski M, Ingber J, de Lacerda LB, Parry B, Ravid S, Clark S, Ho F, Vora SM, Leger V, Beakes C, Margolin J, Russell N, Kays K, Gehrke L, Adhikari UD, Henderson L, Janssen E, Kwon D, Sander C, Abraham J, Filbin M, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Lieberman J. Junqueira C, et al. Among authors: kwon d. Res Sq [Preprint]. 2021 Aug 11:rs.3.rs-153628. doi: 10.21203/rs.3.rs-153628/v1. Res Sq. 2021. PMID: 34401873 Free PMC article. Updated. Preprint.
FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation.
Junqueira C, Crespo Â, Ranjbar S, de Lacerda LB, Lewandrowski M, Ingber J, Parry B, Ravid S, Clark S, Schrimpf MR, Ho F, Beakes C, Margolin J, Russell N, Kays K, Boucau J, Das Adhikari U, Vora SM, Leger V, Gehrke L, Henderson LA, Janssen E, Kwon D, Sander C, Abraham J, Goldberg MB, Wu H, Mehta G, Bell S, Goldfeld AE, Filbin MR, Lieberman J. Junqueira C, et al. Among authors: kwon d. Nature. 2022 Jun;606(7914):576-584. doi: 10.1038/s41586-022-04702-4. Epub 2022 Apr 6. Nature. 2022. PMID: 35385861 Free PMC article.
Metagenomic assessment of gut microbial communities and risk of severe COVID-19.
Lai P, Nguyen L, Okin D, Drew D, Battista V, Jesudasen S, Kuntz T, Bhosle A, Thompson K, Reinicke T, Lo CH, Woo J, Caraballo A, Berra L, Vieira J, Huang CY, Adhikari UD, Kim M, Sui HY, Magicheva-Gupta M, McIver L, Goldberg M, Kwon D, Huttenhower C, Chan A. Lai P, et al. Among authors: kwon d. Res Sq [Preprint]. 2022 Jun 7:rs.3.rs-1717624. doi: 10.21203/rs.3.rs-1717624/v1. Res Sq. 2022. PMID: 35677075 Free PMC article. Updated. Preprint.
Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host.
Choi B, Choudhary MC, Regan J, Sparks JA, Padera RF, Qiu X, Solomon IH, Kuo HH, Boucau J, Bowman K, Adhikari UD, Winkler ML, Mueller AA, Hsu TY, Desjardins M, Baden LR, Chan BT, Walker BD, Lichterfeld M, Brigl M, Kwon DS, Kanjilal S, Richardson ET, Jonsson AH, Alter G, Barczak AK, Hanage WP, Yu XG, Gaiha GD, Seaman MS, Cernadas M, Li JZ. Choi B, et al. Among authors: kwon ds. N Engl J Med. 2020 Dec 3;383(23):2291-2293. doi: 10.1056/NEJMc2031364. Epub 2020 Nov 11. N Engl J Med. 2020. PMID: 33176080 Free PMC article. No abstract available.
Fecal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) RNA Is Associated With Decreased Coronavirus Disease 2019 (COVID-19) Survival.
Das Adhikari U, Eng G, Farcasanu M, Avena LE, Choudhary MC, Triant VA, Flagg M, Schiff AE, Gomez I, Froehle LM, Diefenbach TJ, Ronsard L, Lingwood D, Lee GC, Rabi SA, Erstad D, Velmahos G, Li JZ, Hodin R, Stone JR, Honko AN, Griffiths A, Yilmaz ÖH, Kwon DS. Das Adhikari U, et al. Among authors: kwon ds. Clin Infect Dis. 2022 Mar 23;74(6):1081-1084. doi: 10.1093/cid/ciab623. Clin Infect Dis. 2022. PMID: 34245255 Free PMC article.
SARS-CoV-2 RNA Detected in Vitreous Samples Obtained at Autopsy.
Tieger M, Das Adhikari U, Mukai S, Farcasnu M, Stone JR, Eliott D, Kim LA, Kwon DS, Rossin EJ. Tieger M, et al. Among authors: kwon ds. J Vitreoretin Dis. 2022 May 25;6(3):183-187. doi: 10.1177/24741264221083408. eCollection 2022 May-Jun. J Vitreoretin Dis. 2022. PMID: 37008551 Free PMC article.
Metagenomic assessment of gut microbial communities and risk of severe COVID-19.
Nguyen LH, Okin D, Drew DA, Battista VM, Jesudasen SJ, Kuntz TM, Bhosle A, Thompson KN, Reinicke T, Lo CH, Woo JE, Caraballo A, Berra L, Vieira J, Huang CY, Das Adhikari U, Kim M, Sui HY, Magicheva-Gupta M, McIver L, Goldberg MB, Kwon DS, Huttenhower C, Chan AT, Lai PS. Nguyen LH, et al. Among authors: kwon ds. Genome Med. 2023 Jul 12;15(1):49. doi: 10.1186/s13073-023-01202-6. Genome Med. 2023. PMID: 37438797 Free PMC article.
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.
Metsky HC, Siddle KJ, Gladden-Young A, Qu J, Yang DK, Brehio P, Goldfarb A, Piantadosi A, Wohl S, Carter A, Lin AE, Barnes KG, Tully DC, Corleis B, Hennigan S, Barbosa-Lima G, Vieira YR, Paul LM, Tan AL, Garcia KF, Parham LA, Odia I, Eromon P, Folarin OA, Goba A; Viral Hemorrhagic Fever Consortium; Simon-Lorière E, Hensley L, Balmaseda A, Harris E, Kwon DS, Allen TM, Runstadler JA, Smole S, Bozza FA, Souza TML, Isern S, Michael SF, Lorenzana I, Gehrke L, Bosch I, Ebel G, Grant DS, Happi CT, Park DJ, Gnirke A, Sabeti PC, Matranga CB. Metsky HC, et al. Nat Biotechnol. 2019 Feb;37(2):160-168. doi: 10.1038/s41587-018-0006-x. Epub 2019 Feb 4. Nat Biotechnol. 2019. PMID: 30718881 Free PMC article.
Dysregulation of the Immune Environment in the Airways During HIV Infection.
Bunjun R, Soares AP, Thawer N, Müller TL, Kiravu A, Ginbot Z, Corleis B, Murugan BD, Kwon DS, von Groote-Bidlingmaier F, Riou C, Wilkinson RJ, Walzl G, Burgers WA. Bunjun R, et al. Among authors: kwon ds. Front Immunol. 2021 Jun 30;12:707355. doi: 10.3389/fimmu.2021.707355. eCollection 2021. Front Immunol. 2021. PMID: 34276702 Free PMC article.
2,546 results