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Year Number of Results
1983 1
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1986 1
1987 6
1988 9
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1990 14
1991 16
1992 23
1993 12
1994 18
1995 20
1996 28
1997 31
1998 26
1999 44
2000 28
2001 59
2002 39
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2004 90
2005 105
2006 116
2007 155
2008 167
2009 166
2010 194
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2024 306

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6,828 results

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Page 1
Metabolic engineering for the production of l-phenylalanine in Escherichia coli.
Liu X, Niu H, Li Q, Gu P. Liu X, et al. Among authors: gu p. 3 Biotech. 2019 Mar;9(3):85. doi: 10.1007/s13205-019-1619-6. Epub 2019 Feb 15. 3 Biotech. 2019. PMID: 30800596 Free PMC article. Review.
In this review, successful metabolic engineering strategies for increasing l-phenylalanine accumulation from glucose in E. coli are described. In addition, perspectives for further improvement of production of l-phenylalanine are discussed....
In this review, successful metabolic engineering strategies for increasing l-phenylalanine accumulation from glucose in E. coli are d …
Metabolic engineering for improving L-tryptophan production in Escherichia coli.
Niu H, Li R, Liang Q, Qi Q, Li Q, Gu P. Niu H, et al. Among authors: gu p. J Ind Microbiol Biotechnol. 2019 Jan;46(1):55-65. doi: 10.1007/s10295-018-2106-5. Epub 2018 Nov 13. J Ind Microbiol Biotechnol. 2019. PMID: 30426284 Review.
However, challenges remain for L-tryptophan biosynthesis to be cost-competitive. In this review, successful and applicable strategies derived from metabolic engineering for increasing L-tryptophan accumulation in E. coli are summarized. In addition, perspectives for …
However, challenges remain for L-tryptophan biosynthesis to be cost-competitive. In this review, successful and applicable strategies …
Construction of recombinant Escherichia coli for production of L-phenylalanine-derived compounds.
Liu L, Liu X, Ma Q, Li Q, Gu P. Liu L, et al. Among authors: gu p. World J Microbiol Biotechnol. 2021 Apr 15;37(5):84. doi: 10.1007/s11274-021-03050-1. World J Microbiol Biotechnol. 2021. PMID: 33855641 Review.
L-phenylalanine is an important amino acid that is widely used in the fields of food flavors and pharmaceuticals. Apart from L-phenylalanine itself, various commercially valuable chemical compounds can also be generated via the L-phenylalanine biosynthesis pa …
L-phenylalanine is an important amino acid that is widely used in the fields of food flavors and pharmaceuticals. Apart from L …
Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide.
Xu X, Fukuda T, Takai J, Morii S, Sun Y, Liu J, Ohno S, Isaji T, Yamaguchi Y, Nakano M, Moriguchi T, Gu J. Xu X, et al. Among authors: gu j. J Biol Chem. 2024 Jan;300(1):105513. doi: 10.1016/j.jbc.2023.105513. Epub 2023 Dec 1. J Biol Chem. 2024. PMID: 38042483 Free PMC article.
The activation of microglial cells, which provoke neuroinflammatory responses upon LPS stimulation, was inhibited by l-fucose preadministration. l-Fucose also suppressed the downstream intracellular signaling of IL-6, such as the phosphorylation levels of JAK2 (Janu …
The activation of microglial cells, which provoke neuroinflammatory responses upon LPS stimulation, was inhibited by l-fucose preadmi …
A Meta-Analysis and Systematic Review of Listeria monocytogenes Response to Sanitizer Treatments.
Hu M, Dong Q, Liu Y, Sun T, Gu M, Zhu H, Xia X, Li Z, Wang X, Ma Y, Yang S, Qin X. Hu M, et al. Among authors: gu m. Foods. 2022 Dec 28;12(1):154. doi: 10.3390/foods12010154. Foods. 2022. PMID: 36613373 Free PMC article. Review.
Based on the established model, we compared the response of L. monocytogenes under different hypothetical conditions using forest plots. ...The planktonic cells of L. monocytogenes were less resistant to peracetic acid and sodium hypochlorite than the adherent and b …
Based on the established model, we compared the response of L. monocytogenes under different hypothetical conditions using forest plo …
Unraveling the specific regulation of the shikimate pathway for tyrosine accumulation in Bacillus licheniformis.
Xu Y, Li Y, Zhang L, Ding Z, Gu Z, Shi G. Xu Y, et al. Among authors: gu z. J Ind Microbiol Biotechnol. 2019 Aug;46(8):1047-1059. doi: 10.1007/s10295-019-02213-2. Epub 2019 Jul 11. J Ind Microbiol Biotechnol. 2019. PMID: 31297713 Review.
L-Tyrosine serves as a common precursor for multiple valuable secondary metabolites. ...Quantitative RT-PCR results indicated that aroA, encoding DAHP synthase, and aroK, encoding shikimate kinase, were feedback-repressed by the end product L-tyrosine in the modifie …
L-Tyrosine serves as a common precursor for multiple valuable secondary metabolites. ...Quantitative RT-PCR results indicated that ar …
L-arginine metabolism ameliorates age-related cognitive impairment by Amuc_1100-mediated gut homeostasis maintaining.
He J, Hou T, Wang Q, Wang Q, Jiang Y, Chen L, Xu J, Qi Y, Jia D, Gu Y, Gao L, Yu Y, Wang L, Kang L, Si J, Wang L, Chen S. He J, et al. Among authors: gu y. Aging Cell. 2024 Apr;23(4):e14081. doi: 10.1111/acel.14081. Epub 2024 Jan 18. Aging Cell. 2024. PMID: 38236004 Free PMC article.
Mechanically, Amuc_1100 acted directly as a source of L-arginine and enriched the L-arginine-producing bacteria. In aged brain, Amuc_1100 promoted the superoxide dismutase to alleviated oxidation stress, and increased nitric oxide, derivatives of L-arginine, …
Mechanically, Amuc_1100 acted directly as a source of L-arginine and enriched the L-arginine-producing bacteria. In aged brain …
Cytotoxic Anthracycline Metabolites from a Recombinant Streptomyces.
Gui C, Yuan J, Mo X, Huang H, Zhang S, Gu YC, Ju J. Gui C, et al. Among authors: gu yc. J Nat Prod. 2018 May 25;81(5):1278-1289. doi: 10.1021/acs.jnatprod.8b00212. Epub 2018 May 16. J Nat Prod. 2018. PMID: 29767975
Chemical investigations of this strain's secondary metabolic potential revealed the production of different anthracyclines featuring C7- O-l-rhodinose (or 2-deoxy-l-fucose) instead of the typically observed l-rhodosamine. Purification of the fermentation brot …
Chemical investigations of this strain's secondary metabolic potential revealed the production of different anthracyclines featuring C7- O- …
Antidepressant Actions of Ketamine: Potential Role of L-Type Calcium Channels.
Robinson B, Gu Q, Kanungo J. Robinson B, et al. Among authors: gu q. Chem Res Toxicol. 2021 May 17;34(5):1198-1207. doi: 10.1021/acs.chemrestox.0c00411. Epub 2021 Feb 10. Chem Res Toxicol. 2021. PMID: 33566591 Review.
Often these pathways have been shown to be linked. Voltage-gated L-type calcium channels have been shown to mediate the rapid-acting antidepressant effects of ketamine, especially involving induction of BDNF synthesis downstream, while BDNF deficiency decreases the express …
Often these pathways have been shown to be linked. Voltage-gated L-type calcium channels have been shown to mediate the rapid-acting …
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Koeth RA, Lam-Galvez BR, Kirsop J, Wang Z, Levison BS, Gu X, Copeland MF, Bartlett D, Cody DB, Dai HJ, Culley MK, Li XS, Fu X, Wu Y, Li L, DiDonato JA, Tang WHW, Garcia-Garcia JC, Hazen SL. Koeth RA, et al. Among authors: gu x. J Clin Invest. 2019 Jan 2;129(1):373-387. doi: 10.1172/JCI94601. Epub 2018 Dec 10. J Clin Invest. 2019. PMID: 30530985 Free PMC article. Clinical Trial.
The contribution of gammaBB in gut microbiota-dependent l-carnitine metabolism in humans is unknown. METHODS: Omnivores and vegans/vegetarians ingested deuterium-labeled l-carnitine (d3-l-carnitine) or gammaBB (d9-gammaBB), and both plasma metabolites and fec …
The contribution of gammaBB in gut microbiota-dependent l-carnitine metabolism in humans is unknown. METHODS: Omnivores and vegans/ve …
6,828 results