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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1950 1
1951 3
1952 1
1954 1
1955 2
1956 1
1958 2
1960 1
1964 3
1965 3
1966 1
1967 4
1968 1
1970 4
1971 4
1972 5
1973 2
1974 2
1975 4
1976 5
1977 4
1978 3
1979 2
1980 7
1981 4
1982 11
1983 8
1984 19
1985 10
1986 9
1987 10
1988 15
1989 17
1990 22
1991 21
1992 26
1993 31
1994 36
1995 40
1996 51
1997 50
1998 49
1999 63
2000 78
2001 72
2002 75
2003 79
2004 99
2005 77
2006 105
2007 103
2008 130
2009 139
2010 124
2011 137
2012 153
2013 185
2014 240
2015 252
2016 247
2017 254
2018 326
2019 304
2020 306
2021 345
2022 318
2023 337
2024 115

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4,664 results

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Page 1
L-Glutamine-, peptidyl- and protein-glutaminases: structural features and applications in the food industry.
Martínez YB, Ferreira FV, Musumeci MA. Martínez YB, et al. World J Microbiol Biotechnol. 2022 Aug 25;38(11):204. doi: 10.1007/s11274-022-03391-5. World J Microbiol Biotechnol. 2022. PMID: 36002753 Review.
L-Glutaminases are enzymes that catalyze the cleavage of the gamma-amido bond of L-glutamine residues, producing ammonia and L-glutamate. These enzymes have several applications in food and pharmaceutical industries. However, the L-glutaminases that hy …
L-Glutaminases are enzymes that catalyze the cleavage of the gamma-amido bond of L-glutamine residues, producing ammonia and …
Engineering ergothioneine production in Yarrowia lipolytica.
van der Hoek SA, Rusnák M, Jacobsen IH, Martínez JL, Kell DB, Borodina I. van der Hoek SA, et al. Among authors: martinez jl. FEBS Lett. 2022 May;596(10):1356-1364. doi: 10.1002/1873-3468.14239. Epub 2021 Dec 5. FEBS Lett. 2022. PMID: 34817066 Free PMC article.
We expressed the biosynthetic enzymes EGT1 from Neurospora crassa and EGT2 from Claviceps purpurea to obtain 158 mg.L(-1) of ergothioneine in small-scale cultivation, with an additional copy of each gene improving the titer to 205 mg.L(-1) . The effect of phosphate …
We expressed the biosynthetic enzymes EGT1 from Neurospora crassa and EGT2 from Claviceps purpurea to obtain 158 mg.L(-1) of ergothio …
Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain-Barrier-Permeating Compounds.
Van der Poorten O, Legrand B, Vezenkov LL, García-Pindado J, Bettache N, Knuhtsen A, Pedersen DS, Sánchez-Navarro M, Martinez J, Teixidó M, Garcia M, Tourwé D, Amblard M, Ballet S. Van der Poorten O, et al. Among authors: martinez j. Chembiochem. 2018 Apr 4;19(7):696-705. doi: 10.1002/cbic.201700678. Epub 2018 Feb 28. Chembiochem. 2018. PMID: 29377388
Whereas Boc-[l-Aia-Gly](2,4) -OBn oligomers 12 and 13 and Boc-[l-Aia-beta(3) -h-l-Ala](2,4) -OBn oligomers 16 and 17 were totally or partially disordered, Boc-[l-Aia-l-Ala](2) -OBn (14) induced a typical turn stabilized by C(5) - and C(7) -membe …
Whereas Boc-[l-Aia-Gly](2,4) -OBn oligomers 12 and 13 and Boc-[l-Aia-beta(3) -h-l-Ala](2,4) -OBn oligomers 16 and 17 we …
Initiation of a ZAKalpha-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L.
Xi J, Snieckute G, Martínez JF, Arendrup FSW, Asthana A, Gaughan C, Lund AH, Bekker-Jensen S, Silverman RH. Xi J, et al. Among authors: martinez jf. Cell Rep. 2024 Apr 23;43(4):113998. doi: 10.1016/j.celrep.2024.113998. Epub 2024 Mar 28. Cell Rep. 2024. PMID: 38551960 Free article.
RNase L is an endoribonuclease of higher vertebrates that functions in antiviral innate immunity. Interferons induce oligoadenylate synthetase enzymes that sense double-stranded RNA of viral origin leading to the synthesis of 2',5'-oligoadenylate (2-5A) activators of RNase …
RNase L is an endoribonuclease of higher vertebrates that functions in antiviral innate immunity. Interferons induce oligoadenylate s …
Developing Cardio-Oncology Programs in the New Era: Beyond Ventricular Dysfunction Due to Cancer Treatments.
Pons-Riverola A, Morillas H, Berdejo J, Pernas S, Pomares H, Asiain L, Garay A, Fernandez-Ortega A, Oliveira AC, Martínez E, Jiménez-Marrero S, Pina E, Fort E, Ramos R, Alcoberro L, Hidalgo E, Antonio-Rebollo M, Alcober L, Enjuanes Grau C, Comín-Colet J, Moliner P. Pons-Riverola A, et al. Among authors: martinez e. Cancers (Basel). 2023 Dec 18;15(24):5885. doi: 10.3390/cancers15245885. Cancers (Basel). 2023. PMID: 38136428 Free PMC article. Review.
Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
Maharaj A, Fischer SM, Dillon KN, Kang Y, Martinez MA, Figueroa A. Maharaj A, et al. Among authors: martinez ma. Nutrients. 2022 Oct 20;14(20):4396. doi: 10.3390/nu14204396. Nutrients. 2022. PMID: 36297080 Free PMC article. Clinical Trial.
L-CIT supplementation increased L-ARG levels (delta13 2 vs. delta2 2 mol/L, p < 0.01) and FMD (delta1.4 2.0% vs. delta0.5 1.7%, p = 0.03) compared to PL. ...These findings suggest that L-CIT supplementation improves endothelial function and aortic B …
L-CIT supplementation increased L-ARG levels (delta13 2 vs. delta2 2 mol/L, p < 0.01) and FMD (delta1.4 2.0% vs. del …
Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling.
van der Stel AX, Gordon ER, Sengupta A, Martínez AK, Klepacki D, Perry TN, Herrero Del Valle A, Vázquez-Laslop N, Sachs MS, Cruz-Vera LR, Innis CA. van der Stel AX, et al. Among authors: martinez ak. Nat Commun. 2021 Sep 9;12(1):5340. doi: 10.1038/s41467-021-25663-8. Nat Commun. 2021. PMID: 34504068 Free PMC article.
Free L-tryptophan (L-Trp) stalls ribosomes engaged in the synthesis of TnaC, a leader peptide controlling the expression of the Escherichia coli tryptophanase operon. ...Importantly, the L-Trp binding site is not altered by the R23F mutation, suggesting that …
Free L-tryptophan (L-Trp) stalls ribosomes engaged in the synthesis of TnaC, a leader peptide controlling the expression of th …
Equine enterocytes actively oxidize l-glutamine, but do not synthesize l-citrulline or l-arginine from l-glutamine or l-proline in vitro.
Martinez RE, Leatherwood JL, Bradbery AN, Silvers BL, Fridley J, Arnold CE, Posey EA, He W, Bazer FW, Wu G. Martinez RE, et al. J Anim Sci. 2022 Apr 1;100(4):skac077. doi: 10.1093/jas/skac077. J Anim Sci. 2022. PMID: 35275603 Free PMC article.
Enterocytes were isolated from the jejunum and incubated at 37 C for 30 min in oxygenated (95% O2/5% CO2) Krebs bicarbonate buffer (pH 7.4) containing 5 mM D-glucose and 0 mM, 2-mM L-[U-14C]glutamine, or 2 mM L-[U-14C]proline plus 2 mM L-glutamine. ...
Enterocytes were isolated from the jejunum and incubated at 37 C for 30 min in oxygenated (95% O2/5% CO2) Krebs bicarbonate buffer (pH 7.4) …
4,664 results