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A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer.
Lévi F, Misset JL, Brienza S, Adam R, Metzger G, Itzakhi M, Caussanel JP, Kunstlinger F, Lecouturier S, Descorps-Declère A, et al. Lévi F, et al. Cancer. 1992 Feb 15;69(4):893-900. doi: 10.1002/1097-0142(19920215)69:4<893::aid-cncr2820690410>3.0.co;2-x. Cancer. 1992. PMID: 1735081 Clinical Trial.
Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: a randomized multi-institutional trial.
Lévi FA, Zidani R, Vannetzel JM, Perpoint B, Focan C, Faggiuolo R, Chollet P, Garufi C, Itzhaki M, Dogliotti L, et al. Lévi FA, et al. J Natl Cancer Inst. 1994 Nov 2;86(21):1608-17. doi: 10.1093/jnci/86.21.1608. J Natl Cancer Inst. 1994. PMID: 7932825 Clinical Trial.
Implications of chronobiology for 5-fluorouracil (5-FU) efficacy.
Lévi F, Brienza S, Metzer G, Deprés-Brummer P, Bertheault-Cvitkovic F, Zidani R, Adam R, Misset JL. Lévi F, et al. Adv Exp Med Biol. 1993;339:169-83. doi: 10.1007/978-1-4615-2488-5_18. Adv Exp Med Biol. 1993. PMID: 8178715 Review. No abstract available.
A multicenter evaluation of intensified, ambulatory, chronomodulated chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin as initial treatment of patients with metastatic colorectal carcinoma. International Organization for Cancer Chronotherapy.
Lévi F, Zidani R, Brienza S, Dogliotti L, Perpoint B, Rotarski M, Letourneau Y, Llory JF, Chollet P, Le Rol A, Focan C. Lévi F, et al. Cancer. 1999 Jun 15;85(12):2532-40. doi: 10.1002/(sici)1097-0142(19990615)85:12<2532::aid-cncr7>3.0.co;2-1. Cancer. 1999. PMID: 10375099 Clinical Trial.
956 results