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A Novel MicroRNA Signature for Cholestatic Drugs in Human Hepatocytes and Its Translation into Novel Circulating Biomarkers for Drug-Induced Liver Injury Patients.
Toxicol Sci. 2020 Feb 1;173(2):229-243. doi: 10.1093/toxsci/kfz138.
Toxicol Sci. 2020.
PMID: 31198949
Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.
Donato MT, López-Riera M, Castell JV, Gómez-Lechón MJ, Jover R.
Donato MT, et al. Among authors: lopez riera m.
Toxicol Lett. 2016 Nov 30;263:58-67. doi: 10.1016/j.toxlet.2016.10.008. Epub 2016 Oct 17.
Toxicol Lett. 2016.
PMID: 27765674
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New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease.
López-Riera M, Conde I, Tolosa L, Zaragoza Á, Castell JV, Gómez-Lechón MJ, Jover R.
López-Riera M, et al.
Front Pharmacol. 2017 Jan 25;8:3. doi: 10.3389/fphar.2017.00003. eCollection 2017.
Front Pharmacol. 2017.
PMID: 28179883
Free PMC article.
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Predicting drug-induced cholestasis: preclinical models.
Petrov PD, Fernández-Murga ML, López-Riera M, Goméz-Lechón MJ, Castell JV, Jover R.
Petrov PD, et al. Among authors: lopez riera m.
Expert Opin Drug Metab Toxicol. 2018 Jul;14(7):721-738. doi: 10.1080/17425255.2018.1487399. Epub 2018 Jun 20.
Expert Opin Drug Metab Toxicol. 2018.
PMID: 29888962
Review.
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Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers.
López-Riera M, Conde I, Quintas G, Pedrola L, Zaragoza Á, Perez-Rojas J, Salcedo M, Benlloch S, Castell JV, Jover R.
López-Riera M, et al.
Sci Rep. 2018 Jul 13;8(1):10606. doi: 10.1038/s41598-018-28854-4.
Sci Rep. 2018.
PMID: 30006517
Free PMC article.
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Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium.
López-Riera M, Ortega R, Hueso L, Montesinos MC, Gomez-Cabrera MC, Sanz MJ, Real JT, Piqueras L.
López-Riera M, et al.
Int J Mol Sci. 2021 Aug 27;22(17):9267. doi: 10.3390/ijms22179267.
Int J Mol Sci. 2021.
PMID: 34502180
Free PMC article.
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