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Year | Number of Results |
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2021 | 4 |
2023 | 1 |
2024 | 0 |
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Page 1
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification.
Alzheimers Dement. 2021 Aug;17(8):1365-1382. doi: 10.1002/alz.12302. Epub 2021 Feb 8.
Alzheimers Dement. 2021.
PMID: 33559354
Free PMC article.
Clinical Trial.
A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter.
LaBarbera KM, Sheline YI, Izzo NJ, Yuede CM, Waybright L, Yurko R, Edwards HM, Gardiner WD, Blennow K, Zetterberg H, Börjesson-Hanson A, Morgan R, Davis CS, Guttendorf RJ, Schneider LS, DeKosky S, LeVine H 3rd, Grundman M, Caggiano AO, Cirrito JR, Catalano SM, Hamby ME.
LaBarbera KM, et al.
Transl Neurodegener. 2023 May 12;12(1):24. doi: 10.1186/s40035-023-00358-w.
Transl Neurodegener. 2023.
PMID: 37173791
Free PMC article.
Clinical Trial.
No abstract available.
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Sigma-2 receptor antagonists rescue neuronal dysfunction induced by Parkinson's patient brain-derived α-synuclein.
Limegrover CS, Yurko R, Izzo NJ, LaBarbera KM, Rehak C, Look G, Rishton G, Safferstein H, Catalano SM.
Limegrover CS, et al. Among authors: labarbera km.
J Neurosci Res. 2021 Apr;99(4):1161-1176. doi: 10.1002/jnr.24782. Epub 2021 Jan 22.
J Neurosci Res. 2021.
PMID: 33480104
Free PMC article.
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Modeling the mature CNS: A predictive screening platform for neurodegenerative disease drug discovery.
LaBarbera KM, Limegrover C, Rehak C, Yurko R, Izzo NJ, Knezovich N, Watto E, Waybright L, Catalano SM.
LaBarbera KM, et al.
J Neurosci Methods. 2021 Jul 1;358:109180. doi: 10.1016/j.jneumeth.2021.109180. Epub 2021 Apr 6.
J Neurosci Methods. 2021.
PMID: 33836174
Free PMC article.
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Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer's Disease.
Rishton GM, Look GC, Ni ZJ, Zhang J, Wang Y, Huang Y, Wu X, Izzo NJ, LaBarbera KM, Limegrover CS, Rehak C, Yurko R, Catalano SM.
Rishton GM, et al. Among authors: labarbera km.
ACS Med Chem Lett. 2021 Aug 9;12(9):1389-1395. doi: 10.1021/acsmedchemlett.1c00048. eCollection 2021 Sep 9.
ACS Med Chem Lett. 2021.
PMID: 34531947
Free PMC article.
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