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Enhanced safety and efficacy of protease-regulated CAR-T cell receptors.
Labanieh L, Majzner RG, Klysz D, Sotillo E, Fisher CJ, Vilches-Moure JG, Pacheco KZB, Malipatlolla M, Xu P, Hui JH, Murty T, Theruvath J, Mehta N, Yamada-Hunter SA, Weber EW, Heitzeneder S, Parker KR, Satpathy AT, Chang HY, Lin MZ, Cochran JR, Mackall CL. Labanieh L, et al. Cell. 2022 May 12;185(10):1745-1763.e22. doi: 10.1016/j.cell.2022.03.041. Epub 2022 Apr 27. Cell. 2022. PMID: 35483375 Free PMC article.
High-throughput screening technologies for enzyme engineering.
Longwell CK, Labanieh L, Cochran JR. Longwell CK, et al. Among authors: labanieh l. Curr Opin Biotechnol. 2017 Dec;48:196-202. doi: 10.1016/j.copbio.2017.05.012. Epub 2017 Jun 15. Curr Opin Biotechnol. 2017. PMID: 28624724 Review.
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas.
Mount CW, Majzner RG, Sundaresh S, Arnold EP, Kadapakkam M, Haile S, Labanieh L, Hulleman E, Woo PJ, Rietberg SP, Vogel H, Monje M, Mackall CL. Mount CW, et al. Among authors: labanieh l. Nat Med. 2018 May;24(5):572-579. doi: 10.1038/s41591-018-0006-x. Epub 2018 Apr 16. Nat Med. 2018. PMID: 29662203 Free PMC article.
CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.
Majzner RG, Theruvath JL, Nellan A, Heitzeneder S, Cui Y, Mount CW, Rietberg SP, Linde MH, Xu P, Rota C, Sotillo E, Labanieh L, Lee DW, Orentas RJ, Dimitrov DS, Zhu Z, Croix BS, Delaidelli A, Sekunova A, Bonvini E, Mitra SS, Quezado MM, Majeti R, Monje M, Sorensen PHB, Maris JM, Mackall CL. Majzner RG, et al. Among authors: labanieh l. Clin Cancer Res. 2019 Apr 15;25(8):2560-2574. doi: 10.1158/1078-0432.CCR-18-0432. Epub 2019 Jan 17. Clin Cancer Res. 2019. PMID: 30655315 Free PMC article.
Programming CAR-T cells to kill cancer.
Labanieh L, Majzner RG, Mackall CL. Labanieh L, et al. Nat Biomed Eng. 2018 Jun;2(6):377-391. doi: 10.1038/s41551-018-0235-9. Epub 2018 Jun 11. Nat Biomed Eng. 2018. PMID: 31011197 Review.
Tuning the Antigen Density Requirement for CAR T-cell Activity.
Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL. Majzner RG, et al. Among authors: labanieh l. Cancer Discov. 2020 May;10(5):702-723. doi: 10.1158/2159-8290.CD-19-0945. Epub 2020 Mar 19. Cancer Discov. 2020. PMID: 32193224 Free PMC article.
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Theruvath J, Sotillo E, Mount CW, Graef CM, Delaidelli A, Heitzeneder S, Labanieh L, Dhingra S, Leruste A, Majzner RG, Xu P, Mueller S, Yecies DW, Finetti MA, Williamson D, Johann PD, Kool M, Pfister S, Hasselblatt M, Frühwald MC, Delattre O, Surdez D, Bourdeaut F, Puget S, Zaidi S, Mitra SS, Cheshier S, Sorensen PH, Monje M, Mackall CL. Theruvath J, et al. Among authors: labanieh l. Nat Med. 2020 May;26(5):712-719. doi: 10.1038/s41591-020-0821-8. Epub 2020 Apr 27. Nat Med. 2020. PMID: 32341579 Free PMC article.
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals.
Su Y, Walker JR, Park Y, Smith TP, Liu LX, Hall MP, Labanieh L, Hurst R, Wang DC, Encell LP, Kim N, Zhang F, Kay MA, Casey KM, Majzner RG, Cochran JR, Mackall CL, Kirkland TA, Lin MZ. Su Y, et al. Among authors: labanieh l. Nat Methods. 2020 Aug;17(8):852-860. doi: 10.1038/s41592-020-0889-6. Epub 2020 Jul 13. Nat Methods. 2020. PMID: 32661427 Free PMC article.
29 results