Lacal JC - Search Results

1

Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study.

Ramírez de Molina A, Sarmentero-Estrada J, Belda-Iniesta C, Tarón M, Ramírez de Molina V, Cejas P, Skrzypski M, Gallego-Ortega D, de Castro J, Casado E, García-Cabezas MA, Sánchez JJ, Nistal M, Rosell R, González-Barón M, Lacal JC. Ramírez de Molina A, et al. Among authors: lacal jc. Lancet Oncol. 2007 Oct;8(10):889-97. doi: 10.1016/S1470-2045(07)70279-6. Lancet Oncol. 2007. PMID: 17851129

2

Generation and characterization of monoclonal antibodies against choline kinase alpha and their potential use as diagnostic tools in cancer.

Gallego-Ortega D, Ramirez De Molina A, Gutierrez R, Ramos MA, Sarmentero J, Cejas P, Nistal M, González Barón M, Lacal JC. Gallego-Ortega D, et al. Among authors: lacal jc. Int J Oncol. 2006 Aug;29(2):335-40. Int J Oncol. 2006. PMID: 16820874 Free article.

3

Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.

Ramírez de Molina A, Gallego-Ortega D, Sarmentero-Estrada J, Lagares D, Gómez Del Pulgar T, Bandrés E, García-Foncillas J, Lacal JC. Ramírez de Molina A, et al. Among authors: lacal jc. Int J Biochem Cell Biol. 2008;40(9):1753-63. doi: 10.1016/j.biocel.2008.01.013. Epub 2008 Jan 19. Int J Biochem Cell Biol. 2008. PMID: 18296102

4

TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer.

Valdés-Mora F, Gómez del Pulgar T, Bandrés E, Cejas P, Ramírez de Molina A, Pérez-Palacios R, Gallego-Ortega D, García-Cabezas MA, Casado E, Larrauri J, Nistal M, González-Barón M, García-Foncillas J, Lacal JC. Valdés-Mora F, et al. Among authors: lacal jc. Ann Surg Oncol. 2009 Jan;16(1):78-87. doi: 10.1245/s10434-008-0166-x. Epub 2008 Nov 11. Ann Surg Oncol. 2009. PMID: 19002529

5

Choline kinase alpha depletion selectively kills tumoral cells.

Bañez-Coronel M, Ramírez de Molina A, Rodríguez-González A, Sarmentero J, Ramos MA, García-Cabezas MA, García-Oroz L, Lacal JC. Bañez-Coronel M, et al. Among authors: lacal jc. Curr Cancer Drug Targets. 2008 Dec;8(8):709-19. doi: 10.2174/156800908786733432. Curr Cancer Drug Targets. 2008. PMID: 19075594

6

Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.

Gallego-Ortega D, Ramirez de Molina A, Ramos MA, Valdes-Mora F, Barderas MG, Sarmentero-Estrada J, Lacal JC. Gallego-Ortega D, et al. Among authors: lacal jc. PLoS One. 2009 Nov 12;4(11):e7819. doi: 10.1371/journal.pone.0007819. PLoS One. 2009. PMID: 19915674 Free PMC article.

7

Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.

Ramírez de Molina A, Rodríguez-González A, Gutiérrez R, Martínez-Piñeiro L, Sánchez J, Bonilla F, Rosell R, Lacal J. Ramírez de Molina A, et al. Biochem Biophys Res Commun. 2002 Aug 23;296(3):580-3. doi: 10.1016/s0006-291x(02)00920-8. Biochem Biophys Res Commun. 2002. PMID: 12176020

8

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.

Ramírez de Molina A, Gutiérrez R, Ramos MA, Silva JM, Silva J, Bonilla F, Sánchez JJ, Lacal JC. Ramírez de Molina A, et al. Among authors: lacal jc. Oncogene. 2002 Jun 20;21(27):4317-22. doi: 10.1038/sj.onc.1205556. Oncogene. 2002. PMID: 12082619

9

Phospholipase D and choline kinase: their role in cancer development and their potential as drug targets.

Rodríguez-González A, Ramírez de Molina A, Benítez-Rajal J, Lacal JC. Rodríguez-González A, et al. Among authors: lacal jc. Prog Cell Cycle Res. 2003;5:191-201. Prog Cell Cycle Res. 2003. PMID: 14593713 Review.

10

Inhibition of choline kinase renders a highly selective cytotoxic effect in tumour cells through a mitochondrial independent mechanism.

Rodríguez-González A, Ramírez de Molina A, Bañez-Coronel M, Megias D, Lacal JC. Rodríguez-González A, et al. Among authors: lacal jc. Int J Oncol. 2005 Apr;26(4):999-1008. Int J Oncol. 2005. PMID: 15753995

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