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Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.
Morawe MP, Liao F, Amberg W, van Bergeijk J, Chang R, Gulino M, Hamilton C, Hoft C, Lumpkin C, Mastis B, McGlame E, Nuber J, Plaas C, Ravikumar B, Roy K, Schanzenbächer M, Tierno J, Lakics V, Dellovade T, Townsend M. Morawe MP, et al. Among authors: lakics v. Eur J Pharmacol. 2022 Nov 5;934:175301. doi: 10.1016/j.ejphar.2022.175301. Epub 2022 Sep 30. Eur J Pharmacol. 2022. PMID: 36191631 Free article.
Robust LC3B lipidation analysis by precisely adjusting autophagic flux.
Liebl MP, Meister SC, Frey L, Hendrich K, Klemmer A, Wohlfart B, Untucht C, Nuber J, Pohl C, Lakics V. Liebl MP, et al. Among authors: lakics v. Sci Rep. 2022 Jan 7;12(1):79. doi: 10.1038/s41598-021-03875-8. Sci Rep. 2022. PMID: 34996966 Free PMC article.
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
Petros AM, Korepanova A, Jakob CG, Qiu W, Panchal SC, Wang J, Dietrich JD, Brewer JT, Pohlki F, Kling A, Wilcox K, Lakics V, Bahnassawy L, Reinhardt P, Partha SK, Bodelle PM, Lake M, Charych EI, Stoll VS, Sun C, Mohler EG. Petros AM, et al. Among authors: lakics v. J Med Chem. 2019 Apr 25;62(8):4120-4130. doi: 10.1021/acs.jmedchem.9b00178. Epub 2019 Apr 12. J Med Chem. 2019. PMID: 30933499
Isoform- and cell-state-specific lipidation of ApoE in astrocytes.
Lindner K, Beckenbauer K, van Ek LC, Titeca K, de Leeuw SM, Awwad K, Hanke F, Korepanova AV, Rybin V, van der Kam EL, Mohler EG, Tackenberg C, Lakics V, Gavin AC. Lindner K, et al. Among authors: lakics v. Cell Rep. 2022 Mar 1;38(9):110435. doi: 10.1016/j.celrep.2022.110435. Cell Rep. 2022. PMID: 35235798 Free article.
24 results