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The human skin barrier is organized as stacked bilayers of fully extended ceramides with cholesterol molecules associated with the ceramide sphingoid moiety.
Iwai I, Han H, den Hollander L, Svensson S, Ofverstedt LG, Anwar J, Brewer J, Bloksgaard M, Laloeuf A, Nosek D, Masich S, Bagatolli LA, Skoglund U, Norlén L. Iwai I, et al. Among authors: laloeuf a. J Invest Dermatol. 2012 Sep;132(9):2215-25. doi: 10.1038/jid.2012.43. Epub 2012 Apr 26. J Invest Dermatol. 2012. PMID: 22534876 Free article.