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MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
Chen J, Zheng Q, Hicks JL, Trabzonlu L, Ozbek B, Jones T, Vaghasia AM, Larman TC, Wang R, Markowski MC, Denmeade SR, Pienta KJ, Hruban RH, Antonarakis ES, Gupta A, Dang CV, Yegnasubramanian S, De Marzo AM. Chen J, et al. Among authors: larman tc. JCI Insight. 2023 Dec 22;8(24):e169868. doi: 10.1172/jci.insight.169868. JCI Insight. 2023. PMID: 37971875 Free PMC article.
Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling: IAFs disrupt colon epithelium via PGE2-EP4.
Dong Y, Johnson BA, Ruan L, Zeineldin M, Liu AZ, Raychaudhuri S, Chiu I, Zhu J, Smith B, Zhao N, Searson P, Watanabe S, Donowitz M, Larman TC, Li R. Dong Y, et al. Among authors: larman tc. bioRxiv [Preprint]. 2023 Sep 28:2023.09.28.560060. doi: 10.1101/2023.09.28.560060. bioRxiv. 2023. PMID: 37808771 Free PMC article. Updated. Preprint.
MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
Chen J, Zheng Q, Hicks JL, Trabzonlu L, Ozbek B, Jones T, Vaghasia A, Larman TC, Wang R, Markowski MC, Denmeade SR, Pienta KJ, Hruban RH, Antonarakis ES, Gupta A, Dang CV, Yegnasubramanian S, De Marzo AM. Chen J, et al. Among authors: larman tc. bioRxiv [Preprint]. 2023 Mar 10:2023.02.20.529259. doi: 10.1101/2023.02.20.529259. bioRxiv. 2023. PMID: 36865273 Free PMC article. Updated. Preprint.
Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors.
Shaikh FY, Gills JJ, Mohammad F, White JR, Stevens CM, Ding H, Fu J, Tam A, Blosser RL, Domingue JC, Larman TC, Chaft JE, Spicer JD, Reuss JE, Naidoo J, Forde PM, Ganguly S, Housseau F, Pardoll DM, Sears CL. Shaikh FY, et al. Among authors: larman tc. Cancer Immunol Immunother. 2022 Oct;71(10):2405-2420. doi: 10.1007/s00262-022-03169-6. Epub 2022 Feb 26. Cancer Immunol Immunother. 2022. PMID: 35217892 Free PMC article.
Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models.
Queen J, Domingue JC, White JR, Stevens C, Udayasuryan B, Nguyen TTD, Wu S, Ding H, Fan H, McMann M, Corona A, Larman TC, Verbridge SS, Housseau F, Slade DJ, Drewes JL, Sears CL. Queen J, et al. Among authors: larman tc. mBio. 2021 Feb 22;13(1):e0299121. doi: 10.1128/mbio.02991-21. Epub 2022 Feb 8. mBio. 2021. PMID: 35130731 Free PMC article.
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