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Bis-nor-diterpene from Cnidoscolus quercifolius (Euphorbiaceae) induces tubulin depolymerization-mediated apoptosis in BRAF-mutated melanoma cells.
de Oliveira-Júnior RG, Alves Ferraz CA, de Oliveira AP, da Cruz Araújo EC, Prunier G, Beaugeard L, Groult H, Picot L, de Alencar Filho EB, El Aouad N, Rolim LA, Almeida JRGDS. de Oliveira-Júnior RG, et al. Among authors: beaugeard l. Chem Biol Interact. 2022 Mar 1;355:109849. doi: 10.1016/j.cbi.2022.109849. Epub 2022 Feb 9. Chem Biol Interact. 2022. PMID: 35150652
Polymethoxyflavones from Gardenia oudiepe (Rubiaceae) induce cytoskeleton disruption-mediated apoptosis and sensitize BRAF-mutated melanoma cells to chemotherapy.
Gonçalves de Oliveira-Júnior R, Marcoult-Fréville N, Prunier G, Beaugeard L, Beserra de Alencar Filho E, Simões Mourão ED, Michel S, Quintans-Júnior LJ, Guedes da Silva Almeida JR, Grougnet R, Picot L. Gonçalves de Oliveira-Júnior R, et al. Among authors: beaugeard l. Chem Biol Interact. 2020 Jul 1;325:109109. doi: 10.1016/j.cbi.2020.109109. Epub 2020 May 4. Chem Biol Interact. 2020. PMID: 32376239
Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity.
de Oliveira Júnior RG, Bonnet A, Braconnier E, Groult H, Prunier G, Beaugeard L, Grougnet R, da Silva Almeida JRG, Ferraz CAA, Picot L. de Oliveira Júnior RG, et al. Among authors: beaugeard l. Food Chem Toxicol. 2019 Mar;125:549-561. doi: 10.1016/j.fct.2019.02.013. Epub 2019 Feb 7. Food Chem Toxicol. 2019. PMID: 30738990