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Page 1
BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH.
Nat Metab. 2022 Aug;4(8):1007-1021. doi: 10.1038/s42255-022-00620-x. Epub 2022 Aug 22.
Nat Metab. 2022.
PMID: 35995996
Free PMC article.
Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH.
Bonnet L, Alexandersson I, Baboota RK, Kroon T, Oscarsson J, Smith U, Boucher J.
Bonnet L, et al.
Front Endocrinol (Lausanne). 2022 Aug 22;13:957616. doi: 10.3389/fendo.2022.957616. eCollection 2022.
Front Endocrinol (Lausanne). 2022.
PMID: 36072934
Free PMC article.
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Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.
Khatib Shahidi R, M Hoffmann J, Hedjazifar S, Bonnet L, K Baboota R, Heasman S, Church C, Elias I, Bosch F, Boucher J, Hammarstedt A, Smith U.
Khatib Shahidi R, et al. Among authors: bonnet l.
PLoS One. 2021 Feb 19;16(2):e0247300. doi: 10.1371/journal.pone.0247300. eCollection 2021.
PLoS One. 2021.
PMID: 33606810
Free PMC article.
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PPARγ and PPARα synergize to induce robust browning of white fat in vivo.
Kroon T, Harms M, Maurer S, Bonnet L, Alexandersson I, Lindblom A, Ahnmark A, Nilsson D, Gennemark P, O'Mahony G, Osinski V, McNamara C, Boucher J.
Kroon T, et al. Among authors: bonnet l.
Mol Metab. 2020 Jun;36:100964. doi: 10.1016/j.molmet.2020.02.007. Epub 2020 Feb 18.
Mol Metab. 2020.
PMID: 32248079
Free PMC article.
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Simple Fast Quantification of Cholecalciferol, 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D in Adipose Tissue Using LC-HRMS/MS.
Bonnet L, Margier M, Svilar L, Couturier C, Reboul E, Martin JC, Landrier JF, Defoort C.
Bonnet L, et al.
Nutrients. 2019 Aug 22;11(9):1977. doi: 10.3390/nu11091977.
Nutrients. 2019.
PMID: 31443425
Free PMC article.
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The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH.
Hedjazifar S, Khatib Shahidi R, Hammarstedt A, Bonnet L, Church C, Boucher J, Blüher M, Smith U.
Hedjazifar S, et al. Among authors: bonnet l.
Diabetes. 2020 Mar;69(3):331-341. doi: 10.2337/db19-0701. Epub 2019 Dec 27.
Diabetes. 2020.
PMID: 31882566
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