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2016 2
2018 1
2020 1
2021 1
2024 0

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Page 1
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma.
Cissé MY, Pyrdziak S, Firmin N, Gayte L, Heuillet M, Bellvert F, Fuentes M, Delpech H, Riscal R, Arena G, Chibon F, Le Gellec S, Maran-Gonzalez A, Chateau MC, Theillet C, Carrere S, Portais JC, Le Cam L, Linares LK. Cissé MY, et al. Among authors: gayte l. Sci Transl Med. 2020 Jun 10;12(547):eaay2163. doi: 10.1126/scitranslmed.aay2163. Sci Transl Med. 2020. PMID: 32522803
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Lacroix M, Linares LK, Rueda-Rincon N, Bloch K, Di Michele M, De Blasio C, Fau C, Gayte L, Blanchet E, Mairal A, Derua R, Cardona F, Beuzelin D, Annicotte JS, Pirot N, Torro A, Tinahones FJ, Bernex F, Bertrand-Michel J, Langin D, Fajas L, Swinnen JV, Le Cam L. Lacroix M, et al. Among authors: gayte l. Nat Commun. 2021 Dec 2;12(1):7037. doi: 10.1038/s41467-021-27307-3. Nat Commun. 2021. PMID: 34857760 Free PMC article.
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.
Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L. Arena G, et al. Among authors: gayte l. Mol Cell. 2018 Feb 15;69(4):594-609.e8. doi: 10.1016/j.molcel.2018.01.023. Mol Cell. 2018. PMID: 29452639 Free PMC article.
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity.
Lacroix M, Rodier G, Kirsh O, Houles T, Delpech H, Seyran B, Gayte L, Casas F, Pessemesse L, Heuillet M, Bellvert F, Portais JC, Berthet C, Bernex F, Brivet M, Boutron A, Le Cam L, Sardet C. Lacroix M, et al. Among authors: gayte l. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10998-1003. doi: 10.1073/pnas.1602754113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621446 Free PMC article.
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.
Goguet-Rubio P, Seyran B, Gayte L, Bernex F, Sutter A, Delpech H, Linares LK, Riscal R, Repond C, Rodier G, Kirsh O, Touhami J, Noel J, Vincent C, Pirot N, Pavlovic G, Herault Y, Sitbon M, Pellerin L, Sardet C, Lacroix M, Le Cam L. Goguet-Rubio P, et al. Among authors: gayte l. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11004-9. doi: 10.1073/pnas.1602751113. Epub 2016 Sep 12. Proc Natl Acad Sci U S A. 2016. PMID: 27621431 Free PMC article.