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Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Costantino L, Ferrari S, Santucci M, Salo-Ahen OMH, Carosati E, Franchini S, Lauriola A, Pozzi C, Trande M, Gozzi G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Tagliazucchi L, Moschella MG, Guerrini R, Pacifico S, Luciani R, Genovese F, Henrich S, Alboni S, Santarem N, da Silva Cordeiro A, Giovannetti E, Peters GJ, Pinton P, Rimessi A, Cruciani G, Stroud RM, Wade RC, Mangani S, Marverti G, D'Arca D, Ponterini G, Costi MP. Costantino L, et al. Among authors: lauriola a. Elife. 2022 Dec 7;11:e73862. doi: 10.7554/eLife.73862. Elife. 2022. PMID: 36475542 Free PMC article.
SCFβTrCP-mediated degradation of SHARP1 in triple-negative breast cancer.
Enriqué Steinberg JH, Rossi FA, Magliozzi R, Yuniati L, Santucci M, Rossi M, Guardavaccaro D, Lauriola A. Enriqué Steinberg JH, et al. Among authors: lauriola a. Cell Death Dis. 2023 Nov 8;14(11):726. doi: 10.1038/s41419-023-06253-6. Cell Death Dis. 2023. PMID: 37938564 Free PMC article.
Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy.
Martello A, Lauriola A, Mellis D, Parish E, Dawson JC, Imrie L, Vidmar M, Gammoh N, Mitić T, Brittan M, Mills NL, Carragher NO, D'Arca D, Caporali A. Martello A, et al. Among authors: lauriola a. EMBO Rep. 2020 Jul 3;21(7):e48192. doi: 10.15252/embr.201948192. Epub 2020 Apr 26. EMBO Rep. 2020. PMID: 32337819 Free PMC article.
Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer.
Severi L, Losi L, Fonda S, Taddia L, Gozzi G, Marverti G, Magni F, Chinello C, Stella M, Sheouli J, Braicu EI, Genovese F, Lauriola A, Marraccini C, Gualandi A, D'Arca D, Ferrari S, Costi MP. Severi L, et al. Among authors: lauriola a. Front Pharmacol. 2018 May 8;9:454. doi: 10.3389/fphar.2018.00454. eCollection 2018. Front Pharmacol. 2018. PMID: 29867465 Free PMC article.
28 results