Lazic SE - Search Results

1

Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer.

Weberpals JI, Pugh TJ, Marco-Casanova P, Goss GD, Andrews Wright N, Rath P, Torchia J, Fortuna A, Jones GN, Roudier MP, Bernard L, Lo B, Torti D, Leon A, Marsh K, Hodgson D, Duciaume M, Howat WJ, Lukashchuk N, Lazic SE, Whelan D, Sekhon HS. Weberpals JI, et al. Among authors: lazic se. Cancer Med. 2021 May;10(9):3045-3058. doi: 10.1002/cam4.3831. Epub 2021 Apr 3. Cancer Med. 2021. PMID: 33811746 Free PMC article.

2

Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.

Kvinlaug BT, Chan WI, Bullinger L, Ramaswami M, Sears C, Foster D, Lazic SE, Okabe R, Benner A, Lee BH, De Silva I, Valk PJ, Delwel R, Armstrong SA, Döhner H, Gilliland DG, Huntly BJ. Kvinlaug BT, et al. Among authors: lazic se. Cancer Res. 2011 Jun 15;71(12):4117-29. doi: 10.1158/0008-5472.CAN-11-0176. Epub 2011 Apr 19. Cancer Res. 2011. PMID: 21505102 Free PMC article.

3

Flexible Fitting of PROTAC Concentration-Response Curves with Changepoint Gaussian Processes.

Semenova E, Guerriero ML, Zhang B, Hock A, Hopcroft P, Kadamur G, Afzal AM, Lazic SE. Semenova E, et al. Among authors: lazic se. SLAS Discov. 2021 Oct;26(9):1212-1224. doi: 10.1177/24725552211028142. SLAS Discov. 2021. PMID: 34543136 Free article.

4

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients.

Lazic SE, Goodman AO, Grote HE, Blakemore C, Morton AJ, Hannan AJ, van Dellen A, Barker RA. Lazic SE, et al. Brain Res. 2007 Jun 2;1151:219-26. doi: 10.1016/j.brainres.2007.03.018. Epub 2007 Mar 12. Brain Res. 2007. PMID: 17400200

5

Training in experimental design and statistics is essential: Response to Jordan.

Lazic SE, Clarke-Williams CJ, Munafò MR. Lazic SE, et al. PLoS Biol. 2018 Oct 15;16(10):e3000022. doi: 10.1371/journal.pbio.3000022. eCollection 2018 Oct. PLoS Biol. 2018. PMID: 30321171 Free PMC article.

6

Designing stem-cell-based dopamine cell replacement trials for Parkinson's disease.

Barker RA; TRANSEURO consortium. Barker RA, et al. Nat Med. 2019 Jul;25(7):1045-1053. doi: 10.1038/s41591-019-0507-2. Epub 2019 Jul 1. Nat Med. 2019. PMID: 31263283 Free article.

7

A multi-batch design to deliver robust estimates of efficacy and reduce animal use - a syngeneic tumour case study.

Karp NA, Wilson Z, Stalker E, Mooney L, Lazic SE, Zhang B, Hardaker E. Karp NA, et al. Among authors: lazic se. Sci Rep. 2020 Apr 10;10(1):6178. doi: 10.1038/s41598-020-62509-7. Sci Rep. 2020. PMID: 32277094 Free PMC article.

8

An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington's disease.

Underwood BR, Green-Thompson ZW, Pugh PJ, Lazic SE, Mason SL, Griffin J, Jones PS, Rowe JB, Rubinsztein DC, Barker RA. Underwood BR, et al. Among authors: lazic se. J Neurol. 2017 Dec;264(12):2457-2463. doi: 10.1007/s00415-017-8647-0. Epub 2017 Oct 26. J Neurol. 2017. PMID: 29075837 Free PMC article.

9

Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights.

Lazic SE, Semenova E, Williams DP. Lazic SE, et al. Sci Rep. 2020 Apr 20;10(1):6625. doi: 10.1038/s41598-020-63465-y. Sci Rep. 2020. PMID: 32313041 Free PMC article.

10

Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.

Williams DP, Lazic SE, Foster AJ, Semenova E, Morgan P. Williams DP, et al. Among authors: lazic se. Chem Res Toxicol. 2020 Jan 21;33(1):239-248. doi: 10.1021/acs.chemrestox.9b00264. Epub 2019 Oct 2. Chem Res Toxicol. 2020. PMID: 31535850

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