Le Cras TD - Search Results

1

Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.

Le Cras TD, Korfhagen TR, Davidson C, Schmidt S, Fenchel M, Ikegami M, Whitsett JA, Hardie WD. Le Cras TD, et al. Am J Pathol. 2010 Feb;176(2):679-86. doi: 10.2353/ajpath.2010.090123. Epub 2009 Dec 30. Am J Pathol. 2010. PMID: 20042669 Free PMC article.

2

Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.

Le Cras TD, Hardie WD, Fagan K, Whitsett JA, Korfhagen TR. Le Cras TD, et al. Am J Physiol Lung Cell Mol Physiol. 2003 Nov;285(5):L1046-54. doi: 10.1152/ajplung.00045.2003. Epub 2003 Aug 1. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12896876 Free article.

3

Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis.

Hardie WD, Le Cras TD, Jiang K, Tichelaar JW, Azhar M, Korfhagen TR. Hardie WD, et al. Among authors: le cras td. Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L741-9. doi: 10.1152/ajplung.00208.2003. Epub 2003 Dec 5. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 14660483 Free article.

4

VEGF causes pulmonary hemorrhage, hemosiderosis, and air space enlargement in neonatal mice.

Le Cras TD, Spitzmiller RE, Albertine KH, Greenberg JM, Whitsett JA, Akeson AL. Le Cras TD, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Jul;287(1):L134-42. doi: 10.1152/ajplung.00050.2004. Epub 2004 Mar 19. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15033636 Free article.

5

Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood.

Le Cras TD, Hardie WD, Deutsch GH, Albertine KH, Ikegami M, Whitsett JA, Korfhagen TR. Le Cras TD, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L718-29. doi: 10.1152/ajplung.00084.2004. Epub 2004 Apr 16. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15090366 Free article.

6

Midkine is regulated by hypoxia and causes pulmonary vascular remodeling.

Reynolds PR, Mucenski ML, Le Cras TD, Nichols WC, Whitsett JA. Reynolds PR, et al. Among authors: le cras td. J Biol Chem. 2004 Aug 27;279(35):37124-32. doi: 10.1074/jbc.M405254200. Epub 2004 Jun 14. J Biol Chem. 2004. PMID: 15197188 Free article.

7

Vascular changes after intra-amniotic endotoxin in preterm lamb lungs.

Kallapur SG, Bachurski CJ, Le Cras TD, Joshi SN, Ikegami M, Jobe AH. Kallapur SG, et al. Among authors: le cras td. Am J Physiol Lung Cell Mol Physiol. 2004 Dec;287(6):L1178-85. doi: 10.1152/ajplung.00049.2004. Epub 2004 Aug 20. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15321788 Free article.

8

Vascular endothelial growth factor-A induces prenatal neovascularization and alters bronchial development in mice.

Akeson AL, Cameron JE, Le Cras TD, Whitsett JA, Greenberg JM. Akeson AL, et al. Among authors: le cras td. Pediatr Res. 2005 Jan;57(1):82-8. doi: 10.1203/01.PDR.0000148070.89006.3F. Epub 2004 Nov 19. Pediatr Res. 2005. PMID: 15557114

9

TGF-alpha perturbs surfactant homeostasis in vivo.

Ikegami M, Le Cras TD, Hardie WD, Stahlman MT, Whitsett JA, Korfhagen TR. Ikegami M, et al. Among authors: le cras td. Am J Physiol Lung Cell Mol Physiol. 2005 Jul;289(1):L34-43. doi: 10.1152/ajplung.00407.2004. Epub 2005 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15764643 Free article.

10

Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.

Kramer EL, Deutsch GH, Sartor MA, Hardie WD, Ikegami M, Korfhagen TR, Le Cras TD. Kramer EL, et al. Among authors: le cras td. Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L314-27. doi: 10.1152/ajplung.00354.2006. Epub 2007 Apr 27. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17468132 Free article.

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