LeRoith D - Search Results

1

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.

Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, Deng CX. Xu X, et al. Among authors: leroith d. J Clin Invest. 2006 Jul;116(7):1843-52. doi: 10.1172/JCI27282. Epub 2006 Jun 8. J Clin Invest. 2006. PMID: 16767220 Free PMC article.

2

Absence of the full-length breast cancer-associated gene-1 leads to increased expression of insulin-like growth factor signaling axis members.

Shukla V, Coumoul X, Cao L, Wang RH, Xiao C, Xu X, Andò S, Yakar S, Leroith D, Deng C. Shukla V, et al. Among authors: leroith d. Cancer Res. 2006 Jul 15;66(14):7151-7. doi: 10.1158/0008-5472.CAN-05-4570. Cancer Res. 2006. PMID: 16849561

3

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium.

Dupont J, Renou JP, Shani M, Hennighausen L, LeRoith D. Dupont J, et al. Among authors: leroith d. J Clin Invest. 2002 Sep;110(6):815-25. doi: 10.1172/JCI13829. J Clin Invest. 2002. PMID: 12235113 Free PMC article.

4

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.

Yakar S, Setser J, Zhao H, Stannard B, Haluzik M, Glatt V, Bouxsein ML, Kopchick JJ, LeRoith D. Yakar S, et al. Among authors: leroith d. J Clin Invest. 2004 Jan;113(1):96-105. doi: 10.1172/JCI17763. J Clin Invest. 2004. PMID: 14702113 Free PMC article.

5

Circulating levels of IGF-1 directly regulate bone growth and density.

Yakar S, Rosen CJ, Beamer WG, Ackert-Bicknell CL, Wu Y, Liu JL, Ooi GT, Setser J, Frystyk J, Boisclair YR, LeRoith D. Yakar S, et al. Among authors: leroith d. J Clin Invest. 2002 Sep;110(6):771-81. doi: 10.1172/JCI15463. J Clin Invest. 2002. PMID: 12235108 Free PMC article.

6

Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle.

Fernández AM, Dupont J, Farrar RP, Lee S, Stannard B, Le Roith D. Fernández AM, et al. J Clin Invest. 2002 Feb;109(3):347-55. doi: 10.1172/JCI13503. J Clin Invest. 2002. PMID: 11827994 Free PMC article.

7

Knock your SOCS off!

Leroith D, Nissley P. Leroith D, et al. J Clin Invest. 2005 Feb;115(2):233-6. doi: 10.1172/JCI24228. J Clin Invest. 2005. PMID: 15690080 Free PMC article. Review.

8

Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding.

Lowe WL Jr, Adamo M, Werner H, Roberts CT Jr, LeRoith D. Lowe WL Jr, et al. Among authors: leroith d. J Clin Invest. 1989 Aug;84(2):619-26. doi: 10.1172/JCI114207. J Clin Invest. 1989. PMID: 2547834 Free PMC article.

9

Studies involving the GH-IGF axis: Lessons from IGF-I and IGF-I receptor gene targeting mouse models.

Yakar S, Pennisi P, Kim CH, Zhao H, Toyoshima Y, Gavrilova O, LeRoith D. Yakar S, et al. Among authors: leroith d. J Endocrinol Invest. 2005;28(5 Suppl):19-22. J Endocrinol Invest. 2005. PMID: 16114270 Review.

10

PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells.

Zhao H, Dupont J, Yakar S, Karas M, LeRoith D. Zhao H, et al. Among authors: leroith d. Oncogene. 2004 Jan 22;23(3):786-94. doi: 10.1038/sj.onc.1207162. Oncogene. 2004. PMID: 14737113

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