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Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.
Pereira BI, Devine OP, Vukmanovic-Stejic M, Chambers ES, Subramanian P, Patel N, Virasami A, Sebire NJ, Kinsler V, Valdovinos A, LeSaux CJ, Passos JF, Antoniou A, Rustin MHA, Campisi J, Akbar AN. Pereira BI, et al. Among authors: lesaux cj. Nat Commun. 2019 Jun 3;10(1):2387. doi: 10.1038/s41467-019-10335-5. Nat Commun. 2019. PMID: 31160572 Free PMC article.
Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs.
Calhoun C, Shivshankar P, Saker M, Sloane LB, Livi CB, Sharp ZD, Orihuela CJ, Adnot S, White ES, Richardson A, Le Saux CJ. Calhoun C, et al. J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):153-60. doi: 10.1093/gerona/glu241. Epub 2015 Jan 7. J Gerontol A Biol Sci Med Sci. 2016. PMID: 25568097 Free PMC article.
Calpastatin overexpression impairs postinfarct scar healing in mice by compromising reparative immune cell recruitment and activation.
Wan F, Letavernier E, Le Saux CJ, Houssaini A, Abid S, Czibik G, Sawaki D, Marcos E, Dubois-Rande JL, Baud L, Adnot S, Derumeaux G, Gellen B. Wan F, et al. Am J Physiol Heart Circ Physiol. 2015 Dec 1;309(11):H1883-93. doi: 10.1152/ajpheart.00594.2015. Epub 2015 Oct 9. Am J Physiol Heart Circ Physiol. 2015. PMID: 26453333 Free article.
Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.
Brown AO, Mann B, Gao G, Hankins JS, Humann J, Giardina J, Faverio P, Restrepo MI, Halade GV, Mortensen EM, Lindsey ML, Hanes M, Happel KI, Nelson S, Bagby GJ, Lorent JA, Cardinal P, Granados R, Esteban A, LeSaux CJ, Tuomanen EI, Orihuela CJ. Brown AO, et al. Among authors: lesaux cj. PLoS Pathog. 2014 Sep 18;10(9):e1004383. doi: 10.1371/journal.ppat.1004383. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25232870 Free PMC article.
21 results