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Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G, Tsai CH, Gallart-Ayala H, Yu YR, Franco F, Zaffalon L, Xie X, Li X, Xiao Z, Raines LN, Falquet M, Jalil A, Locasale JW, Percipalle P, Masson D, Huang SC, Martinon F, Ivanisevic J, Ho PC. Di Conza G, et al. Among authors: zaffalon l. Nat Immunol. 2021 Nov;22(11):1403-1415. doi: 10.1038/s41590-021-01047-4. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686867 Free PMC article.
CDC42 regulates PYRIN inflammasome assembly.
Spel L, Zaffalon L, Hou C, Nganko N, Chapuis C, Martinon F. Spel L, et al. Among authors: zaffalon l. Cell Rep. 2022 Nov 15;41(7):111636. doi: 10.1016/j.celrep.2022.111636. Cell Rep. 2022. PMID: 36384121 Free article.
HSP90β controls NLRP3 autoactivation.
Spel L, Hou C, Theodoropoulou K, Zaffalon L, Wang Z, Bertoni A, Volpi S, Hofer M, Gattorno M, Martinon F. Spel L, et al. Among authors: zaffalon l. Sci Adv. 2024 Mar;10(9):eadj6289. doi: 10.1126/sciadv.adj6289. Epub 2024 Feb 28. Sci Adv. 2024. PMID: 38416826 Free PMC article.
The protease DDI2 regulates NRF1 activation in response to cadmium toxicity.
Ribeiro ST, de Gassart A, Bettigole S, Zaffalon L, Chavarria C, Op M, Nugraha K, Martinon F. Ribeiro ST, et al. Among authors: zaffalon l. iScience. 2022 Sep 27;25(10):105227. doi: 10.1016/j.isci.2022.105227. eCollection 2022 Oct 21. iScience. 2022. PMID: 36248746 Free PMC article.
AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Di Micco A, Frera G, Lugrin J, Jamilloux Y, Hsu ET, Tardivel A, De Gassart A, Zaffalon L, Bujisic B, Siegert S, Quadroni M, Broz P, Henry T, Hrycyna CA, Martinon F. Di Micco A, et al. Among authors: zaffalon l. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4671-80. doi: 10.1073/pnas.1602419113. Epub 2016 Jul 26. Proc Natl Acad Sci U S A. 2016. PMID: 27462105 Free PMC article.
11 results