Lear JD - Search Results

1

Computational design of water-soluble analogues of the potassium channel KcsA.

Slovic AM, Kono H, Lear JD, Saven JG, DeGrado WF. Slovic AM, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1828-33. doi: 10.1073/pnas.0306417101. Epub 2004 Feb 6. Proc Natl Acad Sci U S A. 2004. PMID: 14766985 Free PMC article.

2

Sequence determinants of the energetics of folding of a transmembrane four-helix-bundle protein.

Howard KP, Lear JD, DeGrado WF. Howard KP, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8568-72. doi: 10.1073/pnas.132266099. Proc Natl Acad Sci U S A. 2002. PMID: 12084917 Free PMC article.

3

Computational design of a water-soluble analog of phospholamban.

Slovic AM, Summa CM, Lear JD, DeGrado WF. Slovic AM, et al. Among authors: lear jd. Protein Sci. 2003 Feb;12(2):337-48. doi: 10.1110/ps.0226603. Protein Sci. 2003. PMID: 12538897 Free PMC article.

4

Use of thiol-disulfide equilibria to measure the energetics of assembly of transmembrane helices in phospholipid bilayers.

Cristian L, Lear JD, DeGrado WF. Cristian L, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14772-7. doi: 10.1073/pnas.2536751100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657351 Free PMC article.

5

Polar side chains drive the association of model transmembrane peptides.

Gratkowski H, Lear JD, DeGrado WF. Gratkowski H, et al. Among authors: lear jd. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):880-5. doi: 10.1073/pnas.98.3.880. Proc Natl Acad Sci U S A. 2001. PMID: 11158564 Free PMC article.

6

De novo design of a pentameric coiled-coil: decoding the motif for tetramer versus pentamer formation in water-soluble phospholamban.

Slovic AM, Lear JD, DeGrado WF. Slovic AM, et al. Among authors: lear jd. J Pept Res. 2005 Mar;65(3):312-21. doi: 10.1111/j.1399-3011.2005.00244.x. J Pept Res. 2005. PMID: 15787961

7

Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays.

McAllister KA, Zou H, Cochran FV, Bender GM, Senes A, Fry HC, Nanda V, Keenan PA, Lear JD, Saven JG, Therien MJ, Blasie JK, DeGrado WF. McAllister KA, et al. Among authors: lear jd. J Am Chem Soc. 2008 Sep 10;130(36):11921-7. doi: 10.1021/ja800697g. Epub 2008 Aug 19. J Am Chem Soc. 2008. PMID: 18710226 Free PMC article.

8

Experimental and computational evaluation of forces directing the association of transmembrane helices.

Zhang Y, Kulp DW, Lear JD, DeGrado WF. Zhang Y, et al. Among authors: lear jd. J Am Chem Soc. 2009 Aug 19;131(32):11341-3. doi: 10.1021/ja904625b. J Am Chem Soc. 2009. PMID: 19722646

9

Computational design of a self-assembling β-peptide oligomer.

Korendovych IV, Kim YH, Ryan AH, Lear JD, Degrado WF, Shandler SJ. Korendovych IV, et al. Among authors: lear jd. Org Lett. 2010 Nov 19;12(22):5142-5. doi: 10.1021/ol102092r. Epub 2010 Oct 14. Org Lett. 2010. PMID: 20945888 Free PMC article.

10

De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.

Korendovych IV, Senes A, Kim YH, Lear JD, Fry HC, Therien MJ, Blasie JK, Walker FA, Degrado WF. Korendovych IV, et al. Among authors: lear jd. J Am Chem Soc. 2010 Nov 10;132(44):15516-8. doi: 10.1021/ja107487b. J Am Chem Soc. 2010. PMID: 20945900 Free PMC article.

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