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Page 1
Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma.
Seibold T, Schönfelder J, Weeber F, Lechel A, Armacki M, Waldenmaier M, Wille C, Palmer A, Halbgebauer R, Karasu E, Huber-Lang M, Kalbitz M, Radermacher P, Paschke S, Seufferlein T, Eiseler T. Seibold T, et al. Among authors: lechel a. Adv Sci (Weinh). 2021 Dec;8(24):e2102381. doi: 10.1002/advs.202102381. Epub 2021 Oct 28. Adv Sci (Weinh). 2021. PMID: 34713625 Free PMC article.
A Dynamic Role of TBX3 in the Pluripotency Circuitry.
Russell R, Ilg M, Lin Q, Wu G, Lechel A, Bergmann W, Eiseler T, Linta L, Kumar P P, Klingenstein M, Adachi K, Hohwieler M, Sakk O, Raab S, Moon A, Zenke M, Seufferlein T, Schöler HR, Illing A, Liebau S, Kleger A. Russell R, et al. Among authors: lechel a. Stem Cell Reports. 2015 Dec 8;5(6):1155-1170. doi: 10.1016/j.stemcr.2015.11.003. Stem Cell Reports. 2015. PMID: 26651606 Free PMC article.
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.
Armacki M, Trugenberger AK, Ellwanger AK, Eiseler T, Schwerdt C, Bettac L, Langgartner D, Azoitei N, Halbgebauer R, Groß R, Barth T, Lechel A, Walter BM, Kraus JM, Wiegreffe C, Grimm J, Scheffold A, Schneider MR, Peuker K, Zeißig S, Britsch S, Rose-John S, Vettorazzi S, Wolf E, Tannapfel A, Steinestel K, Reber SO, Walther P, Kestler HA, Radermacher P, Barth TF, Huber-Lang M, Kleger A, Seufferlein T. Armacki M, et al. Among authors: lechel a. J Clin Invest. 2018 Nov 1;128(11):5056-5072. doi: 10.1172/JCI97912. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30320600 Free PMC article.
Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice.
Armacki M, Polaschek S, Waldenmaier M, Morawe M, Ruhland C, Schmid R, Lechel A, Tharehalli U, Steup C, Bektas Y, Li H, Kraus JM, Kestler HA, Kruger S, Ormanns S, Walther P, Eiseler T, Seufferlein T. Armacki M, et al. Among authors: lechel a. Gastroenterology. 2020 Sep;159(3):1019-1035.e22. doi: 10.1053/j.gastro.2020.05.052. Epub 2020 May 22. Gastroenterology. 2020. PMID: 32446697 Free article.
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration.
Arnold F, Mahaddalkar PU, Kraus JM, Zhong X, Bergmann W, Srinivasan D, Gout J, Roger E, Beutel AK, Zizer E, Tharehalli U, Daiss N, Russell R, Perkhofer L, Oellinger R, Lin Q, Azoitei N, Weiss FU, Lerch MM, Liebau S, Katz SF, Lechel A, Rad R, Seufferlein T, Kestler HA, Ott M, Sharma AD, Hermann PC, Kleger A. Arnold F, et al. Among authors: lechel a. Adv Sci (Weinh). 2021 May 13;8(14):2100626. doi: 10.1002/advs.202100626. eCollection 2021 Jul. Adv Sci (Weinh). 2021. PMID: 34306986 Free PMC article.
CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variants.
Qiu N, Srikanth A, Mulaw M, Tharehalli U, Selvachandran S, Wagner M, Seufferlein T, Stifter K, Lechel A, Schirmbeck R. Qiu N, et al. Among authors: lechel a. Oncoimmunology. 2023 May 26;12(1):2215096. doi: 10.1080/2162402X.2023.2215096. eCollection 2023. Oncoimmunology. 2023. PMID: 37261086 Free PMC article.
Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld FM, Hessmann E, Gaedcke J, Güthle M, Zenke M, Hartmann D, von Figura G, Weissinger SE, Rudolph KL, Möller P, Lennerz JK, Seufferlein T, Wagner M, Kleger A. Russell R, et al. Among authors: lechel a. Nat Commun. 2015 Jul 29;6:7677. doi: 10.1038/ncomms8677. Nat Commun. 2015. PMID: 26220524 Free PMC article.
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.
Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A. Hohwieler M, et al. Among authors: lechel a. Gut. 2017 Mar;66(3):473-486. doi: 10.1136/gutjnl-2016-312423. Epub 2016 Sep 15. Gut. 2017. PMID: 27633923 Free PMC article.
ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.
Perkhofer L, Schmitt A, Romero Carrasco MC, Ihle M, Hampp S, Ruess DA, Hessmann E, Russell R, Lechel A, Azoitei N, Lin Q, Liebau S, Hohwieler M, Bohnenberger H, Lesina M, Algül H, Gieldon L, Schröck E, Gaedcke J, Wagner M, Wiesmüller L, Sipos B, Seufferlein T, Reinhardt HC, Frappart PO, Kleger A. Perkhofer L, et al. Among authors: lechel a. Cancer Res. 2017 Oct 15;77(20):5576-5590. doi: 10.1158/0008-5472.CAN-17-0634. Epub 2017 Aug 8. Cancer Res. 2017. PMID: 28790064
69 results