Leduc R - Search Results

1

Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses.

Lavenus S, Simard É, Besserer-Offroy É, Froehlich U, Leduc R, Grandbois M. Lavenus S, et al. Among authors: leduc r. Pharmacol Res. 2018 Oct;136:108-120. doi: 10.1016/j.phrs.2018.06.027. Epub 2018 Jun 28. Pharmacol Res. 2018. PMID: 29959993

2

The signaling signature of the neurotensin type 1 receptor with endogenous ligands.

Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Besserer-Offroy É, et al. Among authors: leduc r. Eur J Pharmacol. 2017 Jun 15;805:1-13. doi: 10.1016/j.ejphar.2017.03.046. Epub 2017 Mar 22. Eur J Pharmacol. 2017. PMID: 28341345

3

The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.

Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P. Besserer-Offroy É, et al. Among authors: leduc r. Pharmacol Res. 2018 May;131:7-16. doi: 10.1016/j.phrs.2018.02.032. Epub 2018 Mar 9. Pharmacol Res. 2018. PMID: 29530600

4

Angiotensin II cyclic analogs as tools to investigate AT₁R biased signaling mechanisms.

St-Pierre D, Cabana J, Holleran BJ, Besserer-Offroy É, Escher E, Guillemette G, Lavigne P, Leduc R. St-Pierre D, et al. Among authors: leduc r. Biochem Pharmacol. 2018 Aug;154:104-117. doi: 10.1016/j.bcp.2018.04.021. Epub 2018 Apr 20. Biochem Pharmacol. 2018. PMID: 29684376

5

Interplay between intracellular loop 1 and helix VIII of the angiotensin II type 2 receptor controls its activation.

Connolly A, Holleran BJ, Simard É, Baillargeon JP, Lavigne P, Leduc R. Connolly A, et al. Among authors: leduc r. Biochem Pharmacol. 2019 Oct;168:330-338. doi: 10.1016/j.bcp.2019.07.018. Epub 2019 Jul 23. Biochem Pharmacol. 2019. PMID: 31348898

6

Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation.

Pétigny C, Dumont AA, Giguère H, Collette A, Holleran BJ, Iftinca M, Altier C, Besserer-Offroy É, Auger-Messier M, Leduc R. Pétigny C, et al. Among authors: leduc r. Int J Mol Sci. 2022 Feb 24;23(5):2502. doi: 10.3390/ijms23052502. Int J Mol Sci. 2022. PMID: 35269644 Free PMC article.

7

Elucidation of the structure-activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability.

Murza A, Parent A, Besserer-Offroy E, Tremblay H, Karadereye F, Beaudet N, Leduc R, Sarret P, Marsault É. Murza A, et al. Among authors: leduc r. ChemMedChem. 2012 Feb 6;7(2):318-25. doi: 10.1002/cmdc.201100492. Epub 2011 Dec 13. ChemMedChem. 2012. PMID: 22170700

8

Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.

Fanelli R, Besserer-Offroy É, René A, Côté J, Tétreault P, Collerette-Tremblay J, Longpré JM, Leduc R, Martinez J, Sarret P, Cavelier F. Fanelli R, et al. Among authors: leduc r. J Med Chem. 2015 Oct 8;58(19):7785-95. doi: 10.1021/acs.jmedchem.5b00841. Epub 2015 Sep 16. J Med Chem. 2015. PMID: 26348111

9

Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists.

Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Mona CE, et al. Among authors: leduc r. J Med Chem. 2016 Aug 25;59(16):7512-24. doi: 10.1021/acs.jmedchem.6b00566. Epub 2016 Aug 11. J Med Chem. 2016. PMID: 27434274

10

Design, synthesis, and biological evaluation of CXCR4 ligands.

Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Mona CE, et al. Among authors: leduc r. Org Biomol Chem. 2016 Nov 2;14(43):10298-10311. doi: 10.1039/c6ob01484d. Org Biomol Chem. 2016. PMID: 27752700

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