Lee B - Search Results

1

Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors.

Borys BS, Dang T, So T, Rohani L, Revay T, Walsh T, Thompson M, Argiropoulos B, Rancourt DE, Jung S, Hashimura Y, Lee B, Kallos MS. Borys BS, et al. Among authors: lee b. Stem Cell Res Ther. 2021 Jan 13;12(1):55. doi: 10.1186/s13287-020-02109-4. Stem Cell Res Ther. 2021. PMID: 33436078 Free PMC article.

2

Optimized serial expansion of human induced pluripotent stem cells using low-density inoculation to generate clinically relevant quantities in vertical-wheel bioreactors.

Borys BS, So T, Colter J, Dang T, Roberts EL, Revay T, Larijani L, Krawetz R, Lewis I, Argiropoulos B, Rancourt DE, Jung S, Hashimura Y, Lee B, Kallos MS. Borys BS, et al. Among authors: lee b. Stem Cells Transl Med. 2020 Sep;9(9):1036-1052. doi: 10.1002/sctm.19-0406. Epub 2020 May 22. Stem Cells Transl Med. 2020. PMID: 32445290 Free PMC article.

3

Suspension Culture of Human Induced Pluripotent Stem Cells in Single-Use Vertical-Wheel™ Bioreactors Using Aggregate and Microcarrier Culture Systems.

Nogueira DES, Rodrigues CAV, Hashimura Y, Jung S, Lee B, Cabral JMS. Nogueira DES, et al. Among authors: lee b. Methods Mol Biol. 2021;2286:167-178. doi: 10.1007/7651_2020_287. Methods Mol Biol. 2021. PMID: 33381855

4

Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical-Wheel Bioreactor System: An Experimental and Economic Approach.

de Sousa Pinto D, Bandeiras C, de Almeida Fuzeta M, Rodrigues CAV, Jung S, Hashimura Y, Tseng RJ, Milligan W, Lee B, Ferreira FC, Lobato da Silva C, Cabral JMS. de Sousa Pinto D, et al. Among authors: lee b. Biotechnol J. 2019 Aug;14(8):e1800716. doi: 10.1002/biot.201800716. Epub 2019 May 31. Biotechnol J. 2019. PMID: 30945467

5

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products.

Lee B, Borys BS, Kallos MS, Rodrigues CAV, Silva TP, Cabral JMS. Lee B, et al. Bioengineering (Basel). 2020 Mar 28;7(2):31. doi: 10.3390/bioengineering7020031. Bioengineering (Basel). 2020. PMID: 32231012 Free PMC article.

6

Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products.

Lee B, Jung S, Hashimura Y, Lee M, Borys BS, Dang T, Kallos MS, Rodrigues CAV, Silva TP, Cabral JMS. Lee B, et al. Among authors: lee m. Bioengineering (Basel). 2022 Feb 25;9(3):92. doi: 10.3390/bioengineering9030092. Bioengineering (Basel). 2022. PMID: 35324781 Free PMC article.

7

Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors.

Nogueira DES, Rodrigues CAV, Carvalho MS, Miranda CC, Hashimura Y, Jung S, Lee B, Cabral JMS. Nogueira DES, et al. Among authors: lee b. J Biol Eng. 2019 Sep 14;13:74. doi: 10.1186/s13036-019-0204-1. eCollection 2019. J Biol Eng. 2019. PMID: 31534477 Free PMC article.

8

Transcriptome profiling of human pluripotent stem cell-derived cerebellar organoids reveals faster commitment under dynamic conditions.

Silva TP, Sousa-Luís R, Fernandes TG, Bekman EP, Rodrigues CAV, Vaz SH, Moreira LM, Hashimura Y, Jung S, Lee B, Carmo-Fonseca M, Cabral JMS. Silva TP, et al. Among authors: lee b. Biotechnol Bioeng. 2021 Jul;118(7):2781-2803. doi: 10.1002/bit.27797. Epub 2021 May 3. Biotechnol Bioeng. 2021. PMID: 33871054

9

Scalable Generation of Mature Cerebellar Organoids from Human Pluripotent Stem Cells and Characterization by Immunostaining.

Silva TP, Fernandes TG, Nogueira DES, Rodrigues CAV, Bekman EP, Hashimura Y, Jung S, Lee B, Carmo-Fonseca M, Cabral JMS. Silva TP, et al. Among authors: lee b. J Vis Exp. 2020 Jun 13;(160). doi: 10.3791/61143. J Vis Exp. 2020. PMID: 32597849

10

Production of oncolytic adenovirus and human mesenchymal stem cells in a single-use, Vertical-Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier-based cell culture processes.

Sousa MF, Silva MM, Giroux D, Hashimura Y, Wesselschmidt R, Lee B, Roldão A, Carrondo MJ, Alves PM, Serra M. Sousa MF, et al. Among authors: lee b. Biotechnol Prog. 2015 Nov-Dec;31(6):1600-12. doi: 10.1002/btpr.2158. Epub 2015 Sep 4. Biotechnol Prog. 2015. PMID: 26289142

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