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MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.
Benayoun BA, Lee C. Benayoun BA, et al. Among authors: lee c. Bioessays. 2019 Sep;41(9):e1900046. doi: 10.1002/bies.201900046. Epub 2019 Aug 5. Bioessays. 2019. PMID: 31378979 Free PMC article. Review.
Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition.
D'Souza RF, Woodhead JST, Hedges CP, Zeng N, Wan J, Kumagai H, Lee C, Cohen P, Cameron-Smith D, Mitchell CJ, Merry TL. D'Souza RF, et al. Among authors: lee c. Aging (Albany NY). 2020 Mar 17;12(6):5244-5258. doi: 10.18632/aging.102944. Epub 2020 Mar 17. Aging (Albany NY). 2020. PMID: 32182209 Free PMC article.
Mitochondrial-derived peptides in energy metabolism.
Merry TL, Chan A, Woodhead JST, Reynolds JC, Kumagai H, Kim SJ, Lee C. Merry TL, et al. Among authors: lee c. Am J Physiol Endocrinol Metab. 2020 Oct 1;319(4):E659-E666. doi: 10.1152/ajpendo.00249.2020. Epub 2020 Aug 10. Am J Physiol Endocrinol Metab. 2020. PMID: 32776825 Free PMC article. Review.
MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism.
Lee C, Kim KH, Cohen P. Lee C, et al. Free Radic Biol Med. 2016 Nov;100:182-187. doi: 10.1016/j.freeradbiomed.2016.05.015. Epub 2016 May 20. Free Radic Biol Med. 2016. PMID: 27216708 Free PMC article. Review.
Two additional peptides reported to originate from the mtDNA, namely humanin (Hashimoto et al., 2001; Ikone et al., 2003; Guo et al., 2003) [1-3] and MOTS-c (mitochondrial ORF of the twelve S c) (Lee et al., 2015) [4], indicate a larger mitochondrial genetic …
Two additional peptides reported to originate from the mtDNA, namely humanin (Hashimoto et al., 2001; Ikone et al., 2003; Guo et al., 2003) …
Mitonuclear genomics and aging.
Reynolds JC, Bwiza CP, Lee C. Reynolds JC, et al. Among authors: lee c. Hum Genet. 2020 Mar;139(3):381-399. doi: 10.1007/s00439-020-02119-5. Epub 2020 Jan 29. Hum Genet. 2020. PMID: 31997134 Free PMC article. Review.
Humanin: a harbinger of mitochondrial-derived peptides?
Lee C, Yen K, Cohen P. Lee C, et al. Trends Endocrinol Metab. 2013 May;24(5):222-8. doi: 10.1016/j.tem.2013.01.005. Epub 2013 Feb 8. Trends Endocrinol Metab. 2013. PMID: 23402768 Free PMC article.
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