Lee EJ - Search Results

1

Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency.

Lee EJ, De Winter JM, Buck D, Jasper JR, Malik FI, Labeit S, Ottenheijm CA, Granzier H. Lee EJ, et al. PLoS One. 2013;8(2):e55861. doi: 10.1371/journal.pone.0055861. Epub 2013 Feb 20. PLoS One. 2013. PMID: 23437068 Free PMC article.

2

Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator tirasemtiv.

Lee EJ, Kolb J, Hwee DT, Malik FI, Granzier HL. Lee EJ, et al. Int J Mol Sci. 2019 Oct 10;20(20):5008. doi: 10.3390/ijms20205008. Int J Mol Sci. 2019. PMID: 31658633 Free PMC article.

3

Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy.

Lindqvist J, Lee EJ, Karimi E, Kolb J, Granzier H. Lindqvist J, et al. Among authors: lee ej. PLoS One. 2019 Nov 13;14(11):e0224467. doi: 10.1371/journal.pone.0224467. eCollection 2019. PLoS One. 2019. PMID: 31721788 Free PMC article.

4

Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice.

Lee EJ, Peng J, Radke M, Gotthardt M, Granzier HL. Lee EJ, et al. J Mol Cell Cardiol. 2010 Sep;49(3):449-58. doi: 10.1016/j.yjmcc.2010.05.006. Epub 2010 May 23. J Mol Cell Cardiol. 2010. PMID: 20507834 Free PMC article.

5

Calcium sensitivity and myofilament lattice structure in titin N2B KO mice.

Lee EJ, Nedrud J, Schemmel P, Gotthardt M, Irving TC, Granzier HL. Lee EJ, et al. Arch Biochem Biophys. 2013 Jul 1;535(1):76-83. doi: 10.1016/j.abb.2012.12.004. Epub 2012 Dec 14. Arch Biochem Biophys. 2013. PMID: 23246787 Free PMC article.

6

Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.

Methawasin M, Hutchinson KR, Lee EJ, Smith JE 3rd, Saripalli C, Hidalgo CG, Ottenheijm CA, Granzier H. Methawasin M, et al. Among authors: lee ej. Circulation. 2014 May 13;129(19):1924-36. doi: 10.1161/CIRCULATIONAHA.113.005610. Epub 2014 Mar 5. Circulation. 2014. PMID: 24599837 Free PMC article.

7

Mutation-specific effects on thin filament length in thin filament myopathy.

Winter JM, Joureau B, Lee EJ, Kiss B, Yuen M, Gupta VA, Pappas CT, Gregorio CC, Stienen GJ, Edvardson S, Wallgren-Pettersson C, Lehtokari VL, Pelin K, Malfatti E, Romero NB, Engelen BG, Voermans NC, Donkervoort S, Bönnemann CG, Clarke NF, Beggs AH, Granzier H, Ottenheijm CA. Winter JM, et al. Among authors: lee ej. Ann Neurol. 2016 Jun;79(6):959-69. doi: 10.1002/ana.24654. Epub 2016 Apr 30. Ann Neurol. 2016. PMID: 27074222 Free PMC article.

8

Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle.

Kiss B, Lee EJ, Ma W, Li FW, Tonino P, Mijailovich SM, Irving TC, Granzier HL. Kiss B, et al. Among authors: lee ej. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10369-10374. doi: 10.1073/pnas.1804726115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249654 Free PMC article.

9

Thick-Filament Extensibility in Intact Skeletal Muscle.

Ma W, Gong H, Kiss B, Lee EJ, Granzier H, Irving T. Ma W, et al. Among authors: lee ej. Biophys J. 2018 Oct 16;115(8):1580-1588. doi: 10.1016/j.bpj.2018.08.038. Epub 2018 Sep 4. Biophys J. 2018. PMID: 30266320 Free PMC article.

10

Response to: Thick Filament Length Changes in Muscle Have Both Elastic and Structural Components.

Ma W, Gong H, Kiss B, Lee EJ, Granzier H, Irving T. Ma W, et al. Among authors: lee ej. Biophys J. 2019 Mar 19;116(6):985-986. doi: 10.1016/j.bpj.2019.02.010. Epub 2019 Mar 5. Biophys J. 2019. PMID: 30850114 Free PMC article. No abstract available.

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