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Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCalpha.
Garcia-Bermejo ML, Leskow FC, Fujii T, Wang Q, Blumberg PM, Ohba M, Kuroki T, Han KC, Lee J, Marquez VE, Kazanietz MG. Garcia-Bermejo ML, et al. Among authors: lee j. J Biol Chem. 2002 Jan 4;277(1):645-55. doi: 10.1074/jbc.M107639200. Epub 2001 Oct 2. J Biol Chem. 2002. PMID: 11584014 Free article.
High affinity antagonists of the vanilloid receptor.
Wang Y, Szabo T, Welter JD, Toth A, Tran R, Lee J, Kang SU, Suh YG, Blumberg PM, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2002 Oct;62(4):947-56. doi: 10.1124/mol.62.4.947. Mol Pharmacol. 2002. PMID: 12237342
Conformationally constrained analogues of diacylglycerol. 19. Synthesis and protein kinase C binding affinity of diacylglycerol lactones bearing an N-hydroxylamide side chain.
Choi Y, Kang JH, Lewin NE, Blumberg PM, Lee J, Marquez VE. Choi Y, et al. Among authors: lee j. J Med Chem. 2003 Jun 19;46(13):2790-3. doi: 10.1021/jm030082c. J Med Chem. 2003. PMID: 12801241
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong protein kinase C (PK-C) ligands, were incorrect and correspond instead to esters 2a and 2b, respectively. ...
The structures of N-hydroxylamides 1a and 1b, previously reported by Lee et al. in J. Med. Chem. 2001, 44, 4309-4312 as strong …
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Lee J, Lee J, Kang M, Shin M, Kim JM, Kang SU, Lim JO, Choi HK, Suh YG, Park HG, Oh U, Kim HD, Park YH, Ha HJ, Kim YH, Toth A, Wang Y, Tran R, Pearce LV, Lundberg DJ, Blumberg PM. Lee J, et al. J Med Chem. 2003 Jul 3;46(14):3116-26. doi: 10.1021/jm030089u. J Med Chem. 2003. PMID: 12825950
High-affinity partial agonists of the vanilloid receptor.
Wang Y, Toth A, Tran R, Szabo T, Welter JD, Blumberg PM, Lee J, Kang SU, Lim JO, Lee J. Wang Y, et al. Among authors: lee j. Mol Pharmacol. 2003 Aug;64(2):325-33. doi: 10.1124/mol.64.2.325. Mol Pharmacol. 2003. PMID: 12869637
141,662 results
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