Lee M - Search Results

1

Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation.

Kong LR, Ong RW, Tan TZ, Mohamed Salleh NAB, Thangavelu M, Chan JV, Koh LYJ, Periyasamy G, Lau JA, Le TBU, Wang L, Lee M, Kannan S, Verma CS, Lim CM, Chng WJ, Lane DP, Venkitaraman A, Hung HT, Cheok CF, Goh BC. Kong LR, et al. Among authors: lee m. Nat Commun. 2020 Apr 29;11(1):2086. doi: 10.1038/s41467-020-15608-y. Nat Commun. 2020. PMID: 32350249 Free PMC article.

2

A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis.

Lee M, Venkitaraman AR. Lee M, et al. Cell Cycle. 2014;13(16):2554-63. doi: 10.4161/15384101.2014.942204. Cell Cycle. 2014. PMID: 25486196 Free PMC article.

3

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.

Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, Venkitaraman AR. Pellegrini L, et al. Among authors: lee m. Nature. 2002 Nov 21;420(6913):287-93. doi: 10.1038/nature01230. Epub 2002 Nov 10. Nature. 2002. PMID: 12442171

4

Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.

Lee M, Shorthouse D, Mahen R, Hall BA, Venkitaraman AR. Lee M, et al. Nucleic Acids Res. 2021 Jun 4;49(10):5588-5604. doi: 10.1093/nar/gkab308. Nucleic Acids Res. 2021. PMID: 33978741 Free PMC article.

5

Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA damage and mitotic progression.

Lee M, Daniels MJ, Venkitaraman AR. Lee M, et al. Oncogene. 2004 Jan 29;23(4):865-72. doi: 10.1038/sj.onc.1207223. Oncogene. 2004. PMID: 14647413

6

Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites.

Haas KT, Lee M, Esposito A, Venkitaraman AR. Haas KT, et al. Among authors: lee m. Nucleic Acids Res. 2018 Mar 16;46(5):2398-2416. doi: 10.1093/nar/gkx1303. Nucleic Acids Res. 2018. PMID: 29309696 Free PMC article.

7

BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment.

D'Alessandro G, Whelan DR, Howard SM, Vitelli V, Renaudin X, Adamowicz M, Iannelli F, Jones-Weinert CW, Lee M, Matti V, Lee WTC, Morten MJ, Venkitaraman AR, Cejka P, Rothenberg E, d'Adda di Fagagna F. D'Alessandro G, et al. Among authors: lee m, lee wtc. Nat Commun. 2018 Dec 18;9(1):5376. doi: 10.1038/s41467-018-07799-2. Nat Commun. 2018. PMID: 30560944 Free PMC article.

8

BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance.

Renaudin X, Lee M, Shehata M, Surmann EM, Venkitaraman AR. Renaudin X, et al. Among authors: lee m. Cell Rep. 2021 Aug 3;36(5):109478. doi: 10.1016/j.celrep.2021.109478. Cell Rep. 2021. PMID: 34348152 Free PMC article.

9

Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2.

Daniels MJ, Wang Y, Lee M, Venkitaraman AR. Daniels MJ, et al. Among authors: lee m. Science. 2004 Oct 29;306(5697):876-9. doi: 10.1126/science.1102574. Epub 2004 Sep 16. Science. 2004. PMID: 15375219

10

A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor.

Lee M, Daniels MJ, Garnett MJ, Venkitaraman AR. Lee M, et al. Oncogene. 2011 Jul 28;30(30):3360-9. doi: 10.1038/onc.2011.55. Epub 2011 Mar 14. Oncogene. 2011. PMID: 21399666 Free PMC article.

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