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Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons.
Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, Brunet A, Guillemot F, Chang HY, Wernig M. Wapinski OL, et al. Among authors: lee qy. Cell. 2013 Oct 24;155(3):621-35. doi: 10.1016/j.cell.2013.09.028. Epub 2013 Oct 24. Cell. 2013. PMID: 24243019 Free PMC article.
Generation of induced neuronal cells by the single reprogramming factor ASCL1.
Chanda S, Ang CE, Davila J, Pak C, Mall M, Lee QY, Ahlenius H, Jung SW, Südhof TC, Wernig M. Chanda S, et al. Among authors: lee qy. Stem Cell Reports. 2014 Aug 12;3(2):282-96. doi: 10.1016/j.stemcr.2014.05.020. Epub 2014 Jul 4. Stem Cell Reports. 2014. PMID: 25254342 Free PMC article.
Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons.
Wapinski OL, Lee QY, Chen AC, Li R, Corces MR, Ang CE, Treutlein B, Xiang C, Baubet V, Suchy FP, Sankar V, Sim S, Quake SR, Dahmane N, Wernig M, Chang HY. Wapinski OL, et al. Among authors: lee qy. Cell Rep. 2017 Sep 26;20(13):3236-3247. doi: 10.1016/j.celrep.2017.09.011. Cell Rep. 2017. PMID: 28954238 Free PMC article.
Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes.
Lee QY, Mall M, Chanda S, Zhou B, Sharma KS, Schaukowitch K, Adrian-Segarra JM, Grieder SD, Kareta MS, Wapinski OL, Ang CE, Li R, Südhof TC, Chang HY, Wernig M. Lee QY, et al. Nat Cell Biol. 2020 Apr;22(4):401-411. doi: 10.1038/s41556-020-0490-3. Epub 2020 Mar 30. Nat Cell Biol. 2020. PMID: 32231311
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders.
Ang CE, Ma Q, Wapinski OL, Fan S, Flynn RA, Lee QY, Coe B, Onoguchi M, Olmos VH, Do BT, Dukes-Rimsky L, Xu J, Tanabe K, Wang L, Elling U, Penninger JM, Zhao Y, Qu K, Eichler EE, Srivastava A, Wernig M, Chang HY. Ang CE, et al. Among authors: lee qy. Elife. 2019 Jan 10;8:e41770. doi: 10.7554/eLife.41770. Elife. 2019. PMID: 30628890 Free PMC article.
34 results