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A glycolytic metabolite bypasses "two-hit" tumor suppression by BRCA2.
Kong LR, Gupta K, Wu AJ, Perera D, Ivanyi-Nagy R, Ahmed SM, Tan TZ, Tan SL, Fuddin A, Sundaramoorthy E, Goh GS, Wong RTX, Costa ASH, Oddy C, Wong H, Patro CPK, Kho YS, Huang XZ, Choo J, Shehata M, Lee SC, Goh BC, Frezza C, Pitt JJ, Venkitaraman AR. Kong LR, et al. Among authors: lee sc. Cell. 2024 Apr 25;187(9):2269-2287.e16. doi: 10.1016/j.cell.2024.03.006. Epub 2024 Apr 11. Cell. 2024. PMID: 38608703 Free article.
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma.
Kong LR, Mohamed Salleh NAB, Ong RW, Tan TZ, Syn NL, Goh RM, Fhu CW, Tan DSW, Iyer NG, Kannan S, Verma CS, Lim YC, Soo R, Ho J, Huang Y, Lim JSJ, Yan BJ, Nga ME, Lim SG, Koeffler HP, Lee SC, Kappei D, Hung HT, Goh BC. Kong LR, et al. Among authors: lee sc. Nat Commun. 2020 Mar 25;11(1):1556. doi: 10.1038/s41467-020-15318-5. Nat Commun. 2020. PMID: 32214092 Free PMC article.
Whole Exome Sequencing of Multi-Regional Biopsies from Metastatic Lesions to Evaluate Actionable Truncal Mutations Using a Single-Pass Percutaneous Technique.
Heong V, Tay D, Goh SE, Wee B, Tan TZ, Soo R, Pang B, Lim D, Gopinathan A, Ow S, Chee CE, Goh BC, Lee SC, Yong WP, Wong A, Omar MFM, Soong R, Tan DS. Heong V, et al. Among authors: lee sc. Cancers (Basel). 2020 Jun 17;12(6):1599. doi: 10.3390/cancers12061599. Cancers (Basel). 2020. PMID: 32560395 Free PMC article.
FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites.
Thuya WL, Kong LR, Syn NL, Ding LW, Cheow ESH, Wong RTX, Wang T, Goh RMW, Song H, Jayasinghe MK, Le MT, Hu JC, Yong WP, Lee SC, Wong AL, Sethi G, Hung HT, Ho PC, Thiery JP, Sze SK, Guo T, Soo RA, Yang H, Lim YC, Wang L, Goh BC. Thuya WL, et al. Among authors: lee sc. Theranostics. 2023 Jan 1;13(2):621-638. doi: 10.7150/thno.72297. eCollection 2023. Theranostics. 2023. PMID: 36632230 Free PMC article.
Immunohistochemistry study of tumor vascular normalization and anti-angiogenic effects of sunitinib versus bevacizumab prior to dose-dense doxorubicin/cyclophosphamide chemotherapy in HER2-negative breast cancer.
Yadav K, Lim J, Choo J, Ow SGW, Wong A, Lee M, Chan CW, Hartman M, Lim SE, Ngoi N, Tang SW, Ang Y, Chan G, Chong WQ, Tan HL, Tan SH, Goh BC, Lee SC. Yadav K, et al. Among authors: lee m, lee sc. Breast Cancer Res Treat. 2022 Feb;192(1):131-142. doi: 10.1007/s10549-021-06470-7. Epub 2021 Dec 20. Breast Cancer Res Treat. 2022. PMID: 34928481 Free PMC article. Clinical Trial.
Integration of Antiangiogenic Therapy with Cisplatin and Gemcitabine Chemotherapy in Patients with Nasopharyngeal Carcinoma.
Chong WQ, Lim CM, Sinha AK, Tan CS, Chan GHJ, Huang Y, Kumarakulasinghe NB, Sundar R, Jeyasekharan AD, Loh WS, Tay JK, Yadav K, Wang L, Wong AL, Kong LR, Soo RA, Lau JA, Soon YY, Goh RM, Ho FCH, Chong SM, Lee SC, Loh KS, Tai BC, Lim YC, Goh BC. Chong WQ, et al. Among authors: lee sc. Clin Cancer Res. 2020 Oct 15;26(20):5320-5328. doi: 10.1158/1078-0432.CCR-20-1727. Epub 2020 Aug 14. Clin Cancer Res. 2020. PMID: 32816944 Clinical Trial.
Putting the BRK on breast cancer: From molecular target to therapeutics.
Ang HL, Yuan Y, Lai X, Tan TZ, Wang L, Huang BB, Pandey V, Huang RY, Lobie PE, Goh BC, Sethi G, Yap CT, Chan CW, Lee SC, Kumar AP. Ang HL, et al. Among authors: lee sc. Theranostics. 2021 Jan 1;11(3):1115-1128. doi: 10.7150/thno.49716. eCollection 2021. Theranostics. 2021. PMID: 33391524 Free PMC article. Review.
4,903 results