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Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer.
Chun SK, Fortin BM, Fellows RC, Habowski AN, Verlande A, Song WA, Mahieu AL, Lefebvre AEYT, Sterrenberg JN, Velez LM, Digman MA, Edwards RA, Pannunzio NR, Seldin MM, Waterman ML, Masri S. Chun SK, et al. Among authors: lefebvre aeyt. Sci Adv. 2022 Aug 12;8(32):eabo2389. doi: 10.1126/sciadv.abo2389. Epub 2022 Aug 10. Sci Adv. 2022. PMID: 35947664 Free PMC article.
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing.
Davis RT, Blake K, Ma D, Gabra MBI, Hernandez GA, Phung AT, Yang Y, Maurer D, Lefebvre AEYT, Alshetaiwi H, Xiao Z, Liu J, Locasale JW, Digman MA, Mjolsness E, Kong M, Werb Z, Lawson DA. Davis RT, et al. Among authors: lefebvre aeyt. Nat Cell Biol. 2020 Mar;22(3):310-320. doi: 10.1038/s41556-020-0477-0. Epub 2020 Mar 6. Nat Cell Biol. 2020. PMID: 32144411
Microenvironmental stiffness induces metabolic reprogramming in glioblastoma.
Sohrabi A, Lefebvre AEYT, Harrison MJ, Condro MC, Sanazzaro TM, Safarians G, Solomon I, Bastola S, Kordbacheh S, Toh N, Kornblum HI, Digman MA, Seidlits SK. Sohrabi A, et al. Among authors: lefebvre aeyt. Cell Rep. 2023 Oct 31;42(10):113175. doi: 10.1016/j.celrep.2023.113175. Epub 2023 Sep 26. Cell Rep. 2023. PMID: 37756163 Free PMC article.
The microenvironment dictates glycocalyx construction and immune surveillance.
Tharp KM, Park S, Timblin GA, Richards AL, Berg JA, Twells NM, Riley NM, Peltan EL, Shon DJ, Stevenson E, Tsui K, Palomba F, Lefebvre AEYT, Soens RW, Ayad NME, Hoeve-Scott JT, Healy K, Digman M, Dillin A, Bertozzi CR, Swaney DL, Mahal LK, Cantor JR, Paszek MJ, Weaver VM. Tharp KM, et al. Among authors: lefebvre aeyt. Res Sq [Preprint]. 2023 Aug 16:rs.3.rs-3164966. doi: 10.21203/rs.3.rs-3164966/v1. Res Sq. 2023. PMID: 37645943 Free PMC article. Preprint.
The actin binding protein profilin 1 is critical for mitochondria function.
Read TA, Cisterna BA, Skruber K, Ahmadieh S, Lindamood HL, Vitriol JA, Shi Y, Lefebvre AEYT, Black JB, Butler MT, Bear JE, Cherezova A, Ilatovskaya DV, Weintraub NL, Vitriol EA. Read TA, et al. Among authors: lefebvre aeyt. bioRxiv [Preprint]. 2023 Sep 19:2023.08.07.552354. doi: 10.1101/2023.08.07.552354. bioRxiv. 2023. PMID: 37609280 Free PMC article. Preprint.