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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2002 1
2003 1
2004 2
2005 1
2006 4
2007 4
2008 2
2009 2
2010 7
2011 1
2012 3
2013 8
2014 3
2015 4
2016 6
2017 4
2018 6
2019 2
2020 7
2021 12
2022 15
2023 5
2024 4

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98 results

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Page 1
Activity-Based Screening Assay for Mono-ADP-Ribosylhydrolases.
Wazir S, Maksimainen MM, Alanen HI, Galera-Prat A, Lehtiö L. Wazir S, et al. Among authors: lehtio l. SLAS Discov. 2021 Jan;26(1):67-76. doi: 10.1177/2472555220928911. Epub 2020 Jun 12. SLAS Discov. 2021. PMID: 32527186 Free article.
ADP-ribosyltransferases, an update on function and nomenclature.
Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. Among authors: lehtio l. FEBS J. 2022 Dec;289(23):7399-7410. doi: 10.1111/febs.16142. Epub 2021 Sep 13. FEBS J. 2022. PMID: 34323016 Free PMC article.
Multiple crystal forms of human MacroD2.
Wazir S, Maksimainen MM, Lehtiö L. Wazir S, et al. Among authors: lehtio l. Acta Crystallogr F Struct Biol Commun. 2020 Oct 1;76(Pt 10):477-482. doi: 10.1107/S2053230X20011309. Epub 2020 Sep 15. Acta Crystallogr F Struct Biol Commun. 2020. PMID: 33006575 Free PMC article.
[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
Murthy S, Nizi MG, Maksimainen MM, Massari S, Alaviuhkola J, Lippok BE, Vagaggini C, Sowa ST, Galera-Prat A, Ashok Y, Venkannagari H, Prunskaite-Hyyryläinen R, Dreassi E, Lüscher B, Korn P, Tabarrini O, Lehtiö L. Murthy S, et al. Among authors: lehtio l. J Med Chem. 2023 Jan 26;66(2):1301-1320. doi: 10.1021/acs.jmedchem.2c01460. Epub 2023 Jan 4. J Med Chem. 2023. PMID: 36598465 Free PMC article.
Tankyrases as drug targets.
Lehtiö L, Chi NW, Krauss S. Lehtiö L, et al. FEBS J. 2013 Aug;280(15):3576-93. doi: 10.1111/febs.12320. Epub 2013 Jun 18. FEBS J. 2013. PMID: 23648170 Free article. Review.
A molecular toolbox for ADP-ribosyl binding proteins.
Sowa ST, Galera-Prat A, Wazir S, Alanen HI, Maksimainen MM, Lehtiö L. Sowa ST, et al. Among authors: lehtio l. Cell Rep Methods. 2021 Dec 20;1(8):100121. doi: 10.1016/j.crmeth.2021.100121. Epub 2021 Nov 11. Cell Rep Methods. 2021. PMID: 34786571 Free PMC article.
2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Nkizinkiko Y, Desantis J, Koivunen J, Haikarainen T, Murthy S, Sancineto L, Massari S, Ianni F, Obaji E, Loza MI, Pihlajaniemi T, Brea J, Tabarrini O, Lehtiö L. Nkizinkiko Y, et al. Among authors: lehtio l. Sci Rep. 2018 Jan 26;8(1):1680. doi: 10.1038/s41598-018-19872-3. Sci Rep. 2018. PMID: 29374194 Free PMC article.
98 results