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Did you mean lai yei chen[Author] (14 results)?
Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy.
Chen YJ, Li GN, Li XJ, Wei LX, Fu MJ, Cheng ZL, Yang Z, Zhu GQ, Wang XD, Zhang C, Zhang JY, Sun YP, Saiyin H, Zhang J, Liu WR, Zhu WW, Guan KL, Xiong Y, Yang Y, Ye D, Chen LL. Chen YJ, et al. Among authors: chen ll. Sci Adv. 2023 Apr 28;9(17):eadg0654. doi: 10.1126/sciadv.adg0654. Epub 2023 Apr 28. Sci Adv. 2023. PMID: 37115931 Free PMC article.
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.
Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.
SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.
Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D. Chen XF, et al. Among authors: chen ll. EMBO Rep. 2018 May;19(5):e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28. EMBO Rep. 2018. PMID: 29491006 Free PMC article.
Itaconate in host inflammation and defense.
Ye D, Wang P, Chen LL, Guan KL, Xiong Y. Ye D, et al. Among authors: chen ll. Trends Endocrinol Metab. 2024 Mar 5:S1043-2760(24)00033-X. doi: 10.1016/j.tem.2024.02.004. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 38448252 Review.
Tumour metabolites hinder DNA repair.
Chen LL, Xiong Y. Chen LL, et al. Nature. 2020 Jun;582(7813):492-494. doi: 10.1038/d41586-020-01569-1. Nature. 2020. PMID: 32572248 Free PMC article. No abstract available.
68 results