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Page 1
Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing.
Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2307287120. doi: 10.1073/pnas.2307287120. Epub 2023 Aug 8.
Proc Natl Acad Sci U S A. 2023.
PMID: 37552759
Free PMC article.
DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices.
Liu M, Movahed S, Dangi S, Pan H, Kaur P, Bilinovich SM, Faison EM, Leighton GO, Wang H, Williams DC Jr, Riehn R.
Liu M, et al. Among authors: leighton go.
Epigenetics Chromatin. 2020 Mar 16;13(1):18. doi: 10.1186/s13072-020-00339-7.
Epigenetics Chromatin. 2020.
PMID: 32178718
Free PMC article.
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Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3.
Leighton GO, Irvin EM, Kaur P, Liu M, You C, Bhattaram D, Piehler J, Riehn R, Wang H, Pan H, Williams DC Jr.
Leighton GO, et al.
J Biol Chem. 2022 Oct;298(10):102428. doi: 10.1016/j.jbc.2022.102428. Epub 2022 Aug 28.
J Biol Chem. 2022.
PMID: 36037972
Free PMC article.
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Thermodynamic consequences of Tyr to Trp mutations in the cation-π-mediated binding of trimethyllysine by the HP1 chromodomain.
Krone MW, Albanese KI, Leighton GO, He CQ, Lee GY, Garcia-Borràs M, Guseman AJ, Williams DC Jr, Houk KN, Brustad EM, Waters ML.
Krone MW, et al. Among authors: leighton go.
Chem Sci. 2020 Mar 4;11(13):3495-3500. doi: 10.1039/d0sc00227e.
Chem Sci. 2020.
PMID: 34109021
Free PMC article.
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The folding of the specific DNA recognition subdomain of the sleeping beauty transposase is temperature-dependent and is required for its binding to the transposon DNA.
Leighton GO, Konnova TA, Idiyatullin B, Hurr SH, Zuev YF, Nesmelova IV.
Leighton GO, et al.
PLoS One. 2014 Nov 6;9(11):e112114. doi: 10.1371/journal.pone.0112114. eCollection 2014.
PLoS One. 2014.
PMID: 25375127
Free PMC article.
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