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Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia.
Kogan AA, Topper MJ, Dellomo AJ, Stojanovic L, McLaughlin LJ, Creed TM, Eberly CL, Kingsbury TJ, Baer MR, Kessler MD, Baylin SB, Rassool FV. Kogan AA, et al. Among authors: mclaughlin lj. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2123227119. doi: 10.1073/pnas.2123227119. Epub 2022 Jun 27. Proc Natl Acad Sci U S A. 2022. PMID: 35759659 Free PMC article.
DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation.
Abbotts R, Topper MJ, Biondi C, Fontaine D, Goswami R, Stojanovic L, Choi EY, McLaughlin L, Kogan AA, Xia L, Lapidus R, Mahmood J, Baylin SB, Rassool FV. Abbotts R, et al. Among authors: mclaughlin l. Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22609-22618. doi: 10.1073/pnas.1903765116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591209 Free PMC article.
Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR.
Puts G, Jarrett S, Leonard M, Matsangos N, Snyder D, Wang Y, Vincent R, Portney B, Abbotts R, McLaughlin L, Zalzman M, Rassool F, Kaetzel D. Puts G, et al. Among authors: mclaughlin l. Int J Mol Sci. 2020 Aug 17;21(16):5896. doi: 10.3390/ijms21165896. Int J Mol Sci. 2020. PMID: 32824412 Free PMC article.