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Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas.
Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Antal CE, Downes M, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee JH, Ye Z, Yan H, Hernandez MC, Leiting JL, Evans RM, Ordog T, Truty MJ, Borad MJ, Reya T, Von Hoff DD, Fernandez-Zapico ME, Barrett MT. Lenkiewicz E, et al. Cancer Res. 2020 Oct 15;80(20):4324-4334. doi: 10.1158/0008-5472.CAN-20-0078. Epub 2020 Sep 14. Cancer Res. 2020. PMID: 32928922 Free PMC article.
Advancing a clinically relevant perspective of the clonal nature of cancer.
Ruiz C, Lenkiewicz E, Evers L, Holley T, Robeson A, Kiefer J, Demeure MJ, Hollingsworth MA, Shen M, Prunkard D, Rabinovitch PS, Zellweger T, Mousses S, Trent JM, Carpten JD, Bubendorf L, Von Hoff D, Barrett MT. Ruiz C, et al. Among authors: lenkiewicz e. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12054-9. doi: 10.1073/pnas.1104009108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730190 Free PMC article.
Genomic analysis and selected molecular pathways in rare cancers.
Liu SV, Lenkiewicz E, Evers L, Holley T, Kiefer J, Ruiz C, Glatz K, Bubendorf L, Demeure MJ, Eng C, Ramanathan RK, Von Hoff DD, Barrett MT. Liu SV, et al. Among authors: lenkiewicz e. Phys Biol. 2012 Dec;9(6):065004. doi: 10.1088/1478-3975/9/6/065004. Epub 2012 Nov 29. Phys Biol. 2012. PMID: 23196986
Deep clonal profiling of formalin fixed paraffin embedded clinical samples.
Holley T, Lenkiewicz E, Evers L, Tembe W, Ruiz C, Gsponer JR, Rentsch CA, Bubendorf L, Stapleton M, Amorese D, Legendre C, Cunliffe HE, McCullough AE, Pockaj B, Craig D, Carpten J, Von Hoff D, Iacobuzio-Donahue C, Barrett MT. Holley T, et al. Among authors: lenkiewicz e. PLoS One. 2012;7(11):e50586. doi: 10.1371/journal.pone.0050586. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226320 Free PMC article.
Clonal evolution and therapeutic resistance in solid tumors.
Barrett MT, Lenkiewicz E, Evers L, Holley T, Ruiz C, Bubendorf L, Sekulic A, Ramanathan RK, Von Hoff DD. Barrett MT, et al. Among authors: lenkiewicz e. Front Pharmacol. 2013 Jan 28;4:2. doi: 10.3389/fphar.2013.00002. eCollection 2013. Front Pharmacol. 2013. PMID: 23372550 Free PMC article.
STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma.
Evers L, Perez-Mancera PA, Lenkiewicz E, Tang N, Aust D, Knösel T, Rümmele P, Holley T, Kassner M, Aziz M, Ramanathan RK, Von Hoff DD, Yin H, Pilarsky C, Barrett MT. Evers L, et al. Among authors: lenkiewicz e. Genome Med. 2014 Jan 31;6(1):9. doi: 10.1186/gm526. eCollection 2014. Genome Med. 2014. PMID: 24484537 Free PMC article.
Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.
Egan JB, Barrett MT, Champion MD, Middha S, Lenkiewicz E, Evers L, Francis P, Schmidt J, Shi CX, Van Wier S, Badar S, Ahmann G, Kortuem KM, Boczek NJ, Fonseca R, Craig DW, Carpten JD, Borad MJ, Stewart AK. Egan JB, et al. Among authors: lenkiewicz e. PLoS One. 2014 Feb 5;9(2):e87113. doi: 10.1371/journal.pone.0087113. eCollection 2014. PLoS One. 2014. PMID: 24505276 Free PMC article. Clinical Trial.
71 results