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Year Number of Results
2019 2
2020 6
2021 8
2022 3
2023 5
2024 0

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21 results

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ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, Sparrer KMJ. Hirschenberger M, et al. Among authors: koepke l. Nat Commun. 2023 Nov 1;14(1):6770. doi: 10.1038/s41467-023-42150-4. Nat Commun. 2023. PMID: 37914730 Free PMC article.
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Stürzel CM, Fröhlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R. Thoms M, et al. Among authors: koepke l. Science. 2020 Sep 4;369(6508):1249-1255. doi: 10.1126/science.abc8665. Epub 2020 Jul 17. Science. 2020. PMID: 32680882 Free PMC article.
The antiviral activities of TRIM proteins.
Koepke L, Gack MU, Sparrer KM. Koepke L, et al. Curr Opin Microbiol. 2021 Feb;59:50-57. doi: 10.1016/j.mib.2020.07.005. Epub 2020 Aug 20. Curr Opin Microbiol. 2021. PMID: 32829025 Free PMC article. Review.
Interferon antagonists encoded by SARS-CoV-2 at a glance.
Lee JH, Koepke L, Kirchhoff F, Sparrer KMJ. Lee JH, et al. Among authors: koepke l. Med Microbiol Immunol. 2023 Apr;212(2):125-131. doi: 10.1007/s00430-022-00734-9. Epub 2022 Apr 2. Med Microbiol Immunol. 2023. PMID: 35366686 Free PMC article. Review.
CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins.
Hoenigsperger H, Koepke L, Acharya D, Hunszinger V, Freisem D, Grenzner A, Wiese S, Kirchhoff F, Gack MU, Sparrer KMJ. Hoenigsperger H, et al. Among authors: koepke l. Autophagy. 2023 Nov 8. doi: 10.1080/15548627.2023.2281128. Online ahead of print. Autophagy. 2023. PMID: 37938186
Manipulation of autophagy by SARS-CoV-2 proteins.
Koepke L, Hirschenberger M, Hayn M, Kirchhoff F, Sparrer KM. Koepke L, et al. Autophagy. 2021 Sep;17(9):2659-2661. doi: 10.1080/15548627.2021.1953847. Epub 2021 Jul 19. Autophagy. 2021. PMID: 34281462 Free PMC article.
Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1.
Nchioua R, Schundner A, Klute S, Koepke L, Hirschenberger M, Noettger S, Fois G, Zech F, Graf A, Krebs S, Braubach P, Blum H, Stenger S, Kmiec D, Frick M, Kirchhoff F, Sparrer KM. Nchioua R, et al. Among authors: koepke l. Life Sci Alliance. 2023 Mar 28;6(6):e202201745. doi: 10.26508/lsa.202201745. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 36977594 Free PMC article.
21 results