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A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN.
Wawrzinek R, Wamhoff EC, Lefebre J, Rentzsch M, Bachem G, Domeniconi G, Schulze J, Fuchsberger FF, Zhang H, Modenutti C, Schnirch L, Marti MA, Schwardt O, Bräutigam M, Guberman M, Hauck D, Seeberger PH, Seitz O, Titz A, Ernst B, Rademacher C. Wawrzinek R, et al. Among authors: schnirch l. J Am Chem Soc. 2021 Nov 17;143(45):18977-18988. doi: 10.1021/jacs.1c07235. Epub 2021 Nov 8. J Am Chem Soc. 2021. PMID: 34748320 Free PMC article.
(19)F NMR-Guided Design of Glycomimetic Langerin Ligands.
Wamhoff EC, Hanske J, Schnirch L, Aretz J, Grube M, Varón Silva D, Rademacher C. Wamhoff EC, et al. Among authors: schnirch l. ACS Chem Biol. 2016 Sep 16;11(9):2407-13. doi: 10.1021/acschembio.6b00561. Epub 2016 Aug 3. ACS Chem Biol. 2016. PMID: 27458873
Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Moosmayer D, Hilpmann A, Hoffmann J, Schnirch L, Zimmermann K, Badock V, Furst L, Eaton JK, Viswanathan VS, Schreiber SL, Gradl S, Hillig RC. Moosmayer D, et al. Among authors: schnirch l. Acta Crystallogr D Struct Biol. 2021 Feb 1;77(Pt 2):237-248. doi: 10.1107/S2059798320016125. Epub 2021 Jan 26. Acta Crystallogr D Struct Biol. 2021. PMID: 33559612 Free PMC article.