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811 results

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Page 1
DOT1L inhibitors block abnormal self-renewal induced by cohesin loss.
Heimbruch KE, Fisher JB, Stelloh CT, Phillips E, Reimer MH Jr, Wargolet AJ, Meyer AE, Pulakanti K, Viny AD, Loppnow JJ, Levine RL, Pulikkan JA, Zhu N, Rao S. Heimbruch KE, et al. Among authors: levine rl. Sci Rep. 2021 Mar 31;11(1):7288. doi: 10.1038/s41598-021-86646-9. Sci Rep. 2021. PMID: 33790356 Free PMC article.
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Moran-Crusio K, et al. Among authors: levine rl. Cancer Cell. 2011 Jul 12;20(1):11-24. doi: 10.1016/j.ccr.2011.06.001. Epub 2011 Jun 30. Cancer Cell. 2011. PMID: 21723200 Free PMC article.
Notch pathway activation targets AML-initiating cell homeostasis and differentiation.
Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, Aifantis I. Lobry C, et al. Among authors: levine rl. J Exp Med. 2013 Feb 11;210(2):301-19. doi: 10.1084/jem.20121484. Epub 2013 Jan 28. J Exp Med. 2013. PMID: 23359070 Free PMC article.
Mining the epigenetic landscape in ALL.
Lafave LM, Levine RL. Lafave LM, et al. Among authors: levine rl. Nat Genet. 2013 Nov;45(11):1269-70. doi: 10.1038/ng.2808. Nat Genet. 2013. PMID: 24165727
Genetics of myeloproliferative neoplasms.
Viny AD, Levine RL. Viny AD, et al. Among authors: levine rl. Cancer J. 2014 Jan-Feb;20(1):61-5. doi: 10.1097/PPO.0000000000000013. Cancer J. 2014. PMID: 24445766 Free PMC article. Review.
Genetic alterations of the cohesin complex genes in myeloid malignancies.
Thota S, Viny AD, Makishima H, Spitzer B, Radivoyevitch T, Przychodzen B, Sekeres MA, Levine RL, Maciejewski JP. Thota S, et al. Among authors: levine rl. Blood. 2014 Sep 11;124(11):1790-8. doi: 10.1182/blood-2014-04-567057. Epub 2014 Jul 8. Blood. 2014. PMID: 25006131 Free PMC article. Clinical Trial.
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, Tallman JE, Zhao X, Daniels D, Dai Q, Ciminio L, Aifantis I, He C, Fuks F, Tallman MS, Ferrando A, Nimer S, Paietta E, Thompson CB, Licht JD, Mason CE, Godley LA, Melnick A, Figueroa ME, Levine RL. Rampal R, et al. Among authors: levine rl. Cell Rep. 2014 Dec 11;9(5):1841-1855. doi: 10.1016/j.celrep.2014.11.004. Epub 2014 Dec 4. Cell Rep. 2014. PMID: 25482556 Free PMC article.
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.
Perna F, Vu LP, Themeli M, Kriks S, Hoya-Arias R, Khanin R, Hricik T, Mansilla-Soto J, Papapetrou EP, Levine RL, Studer L, Sadelain M, Nimer SD. Perna F, et al. Among authors: levine rl. Stem Cell Reports. 2015 Apr 14;4(4):658-69. doi: 10.1016/j.stemcr.2015.02.003. Epub 2015 Mar 5. Stem Cell Reports. 2015. PMID: 25754204 Free PMC article.
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.
Viny AD, Ott CJ, Spitzer B, Rivas M, Meydan C, Papalexi E, Yelin D, Shank K, Reyes J, Chiu A, Romin Y, Boyko V, Thota S, Maciejewski JP, Melnick A, Bradner JE, Levine RL. Viny AD, et al. Among authors: levine rl. J Exp Med. 2015 Oct 19;212(11):1819-32. doi: 10.1084/jem.20151317. Epub 2015 Oct 5. J Exp Med. 2015. PMID: 26438361 Free PMC article.
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE. van Galen P, et al. Among authors: levine rl. Mol Cell. 2016 Jan 7;61(1):170-80. doi: 10.1016/j.molcel.2015.11.003. Epub 2015 Dec 10. Mol Cell. 2016. PMID: 26687680 Free PMC article.
811 results