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Page 1
DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Izzo F, Lee SC, Poran A, Chaligne R, Gaiti F, Gross B, Murali RR, Deochand SD, Ang C, Jones PW, Nam AS, Kim KT, Kothen-Hill S, Schulman RC, Ki M, Lhoumaud P, Skok JA, Viny AD, Levine RL, Kenigsberg E, Abdel-Wahab O, Landau DA. Izzo F, et al. Among authors: lhoumaud p. Nat Genet. 2020 Apr;52(4):378-387. doi: 10.1038/s41588-020-0595-4. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203468 Free PMC article.
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.
Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, Hoehn D, Aifantis I. Mullenders J, et al. Among authors: lhoumaud p. J Exp Med. 2015 Oct 19;212(11):1833-50. doi: 10.1084/jem.20151323. Epub 2015 Oct 5. J Exp Med. 2015. PMID: 26438359 Free PMC article.
The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS.
Fragliasso V, Verma A, Manzotti G, Tameni A, Bareja R, Heavican TB, Iqbal J, Wang R, Fiore D, Mularoni V, Chan WC, Lhoumaud P, Skok J, Zanetti E, Merli F, Ciarrocchi A, Elemento O, Inghirami G. Fragliasso V, et al. Among authors: lhoumaud p. Leukemia. 2020 Nov;34(11):2964-2980. doi: 10.1038/s41375-020-0754-8. Epub 2020 Mar 2. Leukemia. 2020. PMID: 32123306
Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.
Liang J, Lacroix L, Gamot A, Cuddapah S, Queille S, Lhoumaud P, Lepetit P, Martin PG, Vogelmann J, Court F, Hennion M, Micas G, Urbach S, Bouchez O, Nöllmann M, Zhao K, Emberly E, Cuvier O. Liang J, et al. Among authors: lhoumaud p. Mol Cell. 2014 Feb 20;53(4):672-81. doi: 10.1016/j.molcel.2013.12.029. Epub 2014 Jan 30. Mol Cell. 2014. PMID: 24486021 Free PMC article.
Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer.
Do C, Jiang G, Cova G, Katsifis CC, Narducci DN, Yang J, Sakellaropoulos T, Vidal R, Lhoumaud P, Fara Regis F, Kakabadze N, Nora EP, Noyes M, Cheng X, Hansen AS, Skok JA. Do C, et al. Among authors: lhoumaud p. bioRxiv [Preprint]. 2024 Feb 5:2024.01.11.575070. doi: 10.1101/2024.01.11.575070. bioRxiv. 2024. PMID: 38370764 Free PMC article. Preprint.
Crosstalk between chromatin and Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage.
Mancheno-Ferris A, Immarigeon C, Rivero A, Depierre D, Schickele N, Fosseprez O, Chanard N, Aughey G, Lhoumaud P, Anglade J, Southall T, Plaza S, Payre F, Cuvier O, Polesello C. Mancheno-Ferris A, et al. Among authors: lhoumaud p. iScience. 2023 Dec 3;27(1):108624. doi: 10.1016/j.isci.2023.108624. eCollection 2024 Jan 19. iScience. 2023. PMID: 38174321 Free PMC article.
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