Li D - Search Results

1

The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.

Yang J, Yan W, Yu Y, Wang Y, Yang T, Xue L, Yuan X, Long C, Liu Z, Chen X, Hu M, Zheng L, Qiu Q, Pei H, Li D, Wang F, Bai P, Wen J, Ye H, Chen L. Yang J, et al. Among authors: li d. J Biol Chem. 2018 Jun 15;293(24):9461-9472. doi: 10.1074/jbc.RA117.001658. Epub 2018 Apr 24. J Biol Chem. 2018. PMID: 29691282 Free PMC article.

2

Malignant Pleural Effusion and ascites Induce Epithelial-Mesenchymal Transition and Cancer Stem-like Cell Properties via the Vascular Endothelial Growth Factor (VEGF)/Phosphatidylinositol 3-Kinase (PI3K)/Akt/Mechanistic Target of Rapamycin (mTOR) Pathway.

Yin T, Wang G, He S, Shen G, Su C, Zhang Y, Wei X, Ye T, Li L, Yang S, Li D, Guo F, Mo Z, Wan Y, Ai P, Zhou X, Liu Y, Wang Y, Wei Y. Yin T, et al. Among authors: li d, li l. J Biol Chem. 2016 Dec 23;291(52):26750-26761. doi: 10.1074/jbc.M116.753236. Epub 2016 Oct 18. J Biol Chem. 2016. PMID: 27756837 Free PMC article.

3

SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules.

Wang F, Zheng L, Yi Y, Yang Z, Qiu Q, Wang X, Yan W, Bai P, Yang J, Li D, Pei H, Niu T, Ye H, Nie C, Hu Y, Yang S, Wei Y, Chen L. Wang F, et al. Among authors: li d. Mol Cancer Ther. 2018 Apr;17(4):763-775. doi: 10.1158/1535-7163.MCT-17-0332. Mol Cancer Ther. 2018. PMID: 29610282

4

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.

Yan W, Yang T, Yang J, Wang T, Yu Y, Wang Y, Chen Q, Bai P, Li D, Ye H, Qiu Q, Zhou Y, Hu Y, Yang S, Wei Y, Li W, Chen L. Yan W, et al. Among authors: li d, li w. Cell Physiol Biochem. 2018;47(2):489-504. doi: 10.1159/000489983. Epub 2018 May 22. Cell Physiol Biochem. 2018. PMID: 29794416 Free article.

5

Biodegradable Interlayer-Crosslinked Polymer Micelles with Reduction Sensitivity for Non-Small Cell Lung Cancer Therapy.

Wang Z, Wen J, Liu H, Zheng L, Luo H, Liu Z, Chen X, Wang F, Li D, Pei H, Li W, Chen L. Wang Z, et al. Among authors: li d, li w. J Biomed Nanotechnol. 2018 Jul 1;14(7):1225-1238. doi: 10.1166/jbn.2018.2538. J Biomed Nanotechnol. 2018. PMID: 29944097

6

Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer.

Tang H, Zhang Y, Li D, Fu S, Tang M, Wan L, Chen K, Liu Z, Xue L, Peng A, Ye H, Chen L. Tang H, et al. Among authors: li d. Eur J Med Chem. 2018 Aug 5;156:190-205. doi: 10.1016/j.ejmech.2018.06.048. Epub 2018 Jun 27. Eur J Med Chem. 2018. PMID: 30006164

7

PEG-derivatized birinapant as a nanomicellar carrier of paclitaxel delivery for cancer therapy.

Shu X, Zhu Z, Cao D, Zheng L, Wang F, Pei H, Wen J, Yang J, Li D, Bai P, Tang M, Ye H, Peng A, Li W, Chen L. Shu X, et al. Among authors: li d, li w. Colloids Surf B Biointerfaces. 2019 Oct 1;182:110356. doi: 10.1016/j.colsurfb.2019.110356. Epub 2019 Jul 13. Colloids Surf B Biointerfaces. 2019. PMID: 31319226

8

Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.

Wang L, Zheng Y, Li D, Yang J, Lei L, Yan W, Zheng W, Tang M, Shi M, Zhang R, Cai X, Ni H, Ma X, Li N, Hong F, Ye H, Chen L. Wang L, et al. Among authors: li d, li n. J Med Chem. 2021 Jun 24;64(12):8127-8141. doi: 10.1021/acs.jmedchem.0c01961. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34081857

9

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.

Liu K, Li D, Zheng W, Shi M, Chen Y, Tang M, Yang T, Zhao M, Deng D, Zhang C, Liu J, Yuan X, Yang Z, Chen L. Liu K, et al. Among authors: li d. J Med Chem. 2021 Jul 8;64(13):8951-8970. doi: 10.1021/acs.jmedchem.1c00004. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138567

10

Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Zhu Z, Wen J, Xu Y, Pei H, Li D, Tang M, Bai P, He J, Yang Z, Chen L. Zhu Z, et al. Among authors: li d. Ann Med. 2022 Dec;54(1):743-753. doi: 10.1080/07853890.2022.2045347. Ann Med. 2022. PMID: 35243950 Free PMC article.

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