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Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR.
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X. Jiang Z, et al. Among authors: li x. J Biol Chem. 2003 May 9;278(19):16713-9. doi: 10.1074/jbc.M300562200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12609980 Free article.
NFkappaB-dependent signaling pathways.
Li X, Stark GR. Li X, et al. Exp Hematol. 2002 Apr;30(4):285-96. doi: 10.1016/s0301-472x(02)00777-4. Exp Hematol. 2002. PMID: 11937262 Free article. Review.
Mutant human cells with constitutive activation of NF-kappaB.
Sathe SS, Sizemore N, Li X, Vithalani K, Commane M, Swiatkowski SM, Stark GR. Sathe SS, et al. Among authors: li x. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):192-7. doi: 10.1073/pnas.0306812101. Epub 2003 Dec 22. Proc Natl Acad Sci U S A. 2004. PMID: 14691254 Free PMC article.
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