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Cigarette smoke exposure enhances transforming acidic coiled-coil-containing protein 2 turnover and thereby promotes emphysema.
Mallampalli RK, Li X, Jang JH, Kaminski T, Hoji A, Coon T, Chandra D, Welty S, Teng Y, Sembrat J, Rojas M, Zhao Y, Lafyatis R, Zou C, Sciurba F, Sundd P, Lan L, Nyunoya T. Mallampalli RK, et al. Among authors: li x. JCI Insight. 2020 Jan 30;5(2):e125895. doi: 10.1172/jci.insight.125895. JCI Insight. 2020. PMID: 31996486 Free PMC article.
Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD.
Li X, Noell G, Tabib T, Gregory AD, Trejo Bittar HE, Vats R, Kaminski TW, Sembrat J, Snyder ME, Chandra D, Chen K, Zou C, Zhang Y, Sundd P, McDyer JF, Sciurba F, Rojas M, Lafyatis R, Shapiro SD, Faner R, Nyunoya T. Li X, et al. Respir Res. 2021 Apr 6;22(1):100. doi: 10.1186/s12931-021-01675-2. Respir Res. 2021. PMID: 33823868 Free PMC article.
Cigarette smoking is a secondary cause of folliculin loss.
Li X, Lai Y, Lane Z, Strollo H, Tanimura K, Sembrat JC, Zou C, Myerburg MM, Rojas M, Shapiro S, Jiang Y, Nyunoya T. Li X, et al. Thorax. 2023 Apr;78(4):402-408. doi: 10.1136/thoraxjnl-2021-217197. Epub 2022 Mar 17. Thorax. 2023. PMID: 35301243 Free PMC article.
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