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Dihydroceramides: From Bit Players to Lead Actors.
Siddique MM, Li Y, Chaurasia B, Kaddai VA, Summers SA. Siddique MM, et al. Among authors: li y. J Biol Chem. 2015 Jun 19;290(25):15371-15379. doi: 10.1074/jbc.R115.653204. Epub 2015 May 6. J Biol Chem. 2015. PMID: 25947377 Free PMC article. Review.
Ceramide signaling in the gut.
Li Y, Nicholson RJ, Summers SA. Li Y, et al. Mol Cell Endocrinol. 2022 Mar 15;544:111554. doi: 10.1016/j.mce.2022.111554. Epub 2022 Jan 5. Mol Cell Endocrinol. 2022. PMID: 34998898 Free PMC article. Review.
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Among authors: li y. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.
Gutting out Myc to decrease ceramides.
Li Y, Summers SA, Holland WL. Li Y, et al. Nat Metab. 2021 Jul;3(7):890-891. doi: 10.1038/s42255-021-00418-3. Nat Metab. 2021. PMID: 34211181 Free PMC article.
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