Li Z - Search Results

1

Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors.

Halland N, Schmidt F, Weiss T, Saas J, Li Z, Czech J, Dreyer M, Hofmeister A, Mertsch K, Dietz U, Strübing C, Nazare M. Halland N, et al. Among authors: li z. ACS Med Chem Lett. 2014 Oct 23;6(1):73-8. doi: 10.1021/ml5003376. eCollection 2015 Jan 8. ACS Med Chem Lett. 2014. PMID: 25589934 Free PMC article.

2

Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis.

Halland N, Schmidt F, Weiss T, Li Z, Czech J, Saas J, Ding-Pfennigdorff D, Dreyer MK, Strübing C, Nazare M. Halland N, et al. Among authors: li z. J Med Chem. 2022 Jan 27;65(2):1567-1584. doi: 10.1021/acs.jmedchem.1c01601. Epub 2021 Dec 21. J Med Chem. 2022. PMID: 34931844

3

Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic siRNA Targeting and Stabilization.

Hofmeister A, Jahn-Hofmann K, Brunner B, Helms MW, Metz-Weidmann C, Krack A, Kurz M, Li Z, Weitzenberg MM, Pflimlin E, Plettenburg O, Scheidler S. Hofmeister A, et al. Among authors: li z. J Med Chem. 2021 May 27;64(10):6838-6855. doi: 10.1021/acs.jmedchem.1c00144. Epub 2021 May 5. J Med Chem. 2021. PMID: 33950677

4

Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).

Méndez M, Matter H, Defossa E, Kurz M, Lebreton S, Li Z, Lohmann M, Löhn M, Mors H, Podeschwa M, Rackelmann N, Riedel J, Safar P, Thorpe DS, Schäfer M, Weitz D, Breitschopf K. Méndez M, et al. Among authors: li z. J Med Chem. 2020 Mar 12;63(5):2292-2307. doi: 10.1021/acs.jmedchem.9b01071. Epub 2019 Oct 23. J Med Chem. 2020. PMID: 31596080

5

Automated Design of Macrocycles for Therapeutic Applications: From Small Molecules to Peptides and Proteins.

Sindhikara D, Wagner M, Gkeka P, Güssregen S, Tiwari G, Hessler G, Yapici E, Li Z, Evers A. Sindhikara D, et al. Among authors: li z. J Med Chem. 2020 Oct 22;63(20):12100-12115. doi: 10.1021/acs.jmedchem.0c01500. Epub 2020 Oct 5. J Med Chem. 2020. PMID: 33017535

6

Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening.

McLean LR, Zhang Y, Li H, Li Z, Lukasczyk U, Choi YM, Han Z, Prisco J, Fordham J, Tsay JT, Reiling S, Vaz RJ, Li Y. McLean LR, et al. Among authors: li y, li z, li h. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6717-20. doi: 10.1016/j.bmcl.2009.09.106. Epub 2009 Oct 1. Bioorg Med Chem Lett. 2009. PMID: 19836948

7

Discovery and pharmacological characterization of a novel small molecule inhibitor of phosphatidylinositol-5-phosphate 4-kinase, type II, beta.

Voss MD, Czechtizky W, Li Z, Rudolph C, Petry S, Brummerhop H, Langer T, Schiffer A, Schaefer HL. Voss MD, et al. Among authors: li z. Biochem Biophys Res Commun. 2014 Jul 4;449(3):327-31. doi: 10.1016/j.bbrc.2014.05.024. Epub 2014 May 15. Biochem Biophys Res Commun. 2014. PMID: 24845568

8

An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics.

Furtmann N, Schneider M, Spindler N, Steinmann B, Li Z, Focken I, Meyer J, Dimova D, Kroll K, Leuschner WD, Debeaumont A, Mathieu M, Lange C, Dittrich W, Kruip J, Schmidt T, Birkenfeld J. Furtmann N, et al. Among authors: li z. MAbs. 2021 Jan-Dec;13(1):1955433. doi: 10.1080/19420862.2021.1955433. MAbs. 2021. PMID: 34382900 Free PMC article.

9

Ustilipids, acylated beta-D-mannopyranosyl D-erythritols from Ustilago maydis and Geotrichum candidum.

Kurz M, Eder C, Isert D, Li Z, Paulus EF, Schiell M, Toti L, Vértesy L, Wink J, Seibert G. Kurz M, et al. Among authors: li z. J Antibiot (Tokyo). 2003 Feb;56(2):91-101. doi: 10.7164/antibiotics.56.91. J Antibiot (Tokyo). 2003. PMID: 12715867 Free article.

10

High-throughput screening assay for the quantification of Cer d18:1/16:0, d18:1/24:0, d18:1/24:1, d18:1/18:0, d18:1/14:0, d18:1/20:0, and d18:1/22:0 in HepG2 cells using RapidFire mass spectrometry.

Dittakavi S, Mahadevan L, Chandrashekar DV, Bhamidipati RK, Suresh J, Dhakshinamoorthy S, Li Z, Baerenz F, Tennagels N, Mullangi R. Dittakavi S, et al. Among authors: li z. Biomed Chromatogr. 2020 May;34(5):e4790. doi: 10.1002/bmc.4790. Epub 2020 Feb 25. Biomed Chromatogr. 2020. PMID: 31883352

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