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Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.
Li Z, Ferguson L, Deol KK, Roberts MA, Magtanong L, Hendricks JM, Mousa GA, Kilinc S, Schaefer K, Wells JA, Bassik MC, Goga A, Dixon SJ, Ingolia NT, Olzmann JA. Li Z, et al. Nat Chem Biol. 2022 Jul;18(7):751-761. doi: 10.1038/s41589-022-01033-3. Epub 2022 May 30. Nat Chem Biol. 2022. PMID: 35637349 Free PMC article.
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.
Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA. Bersuker K, et al. Among authors: li z. Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21. Nature. 2019. PMID: 31634900 Free PMC article.
Going through a phase.
Li Z, Morris SNS, Olzmann JA. Li Z, et al. Nat Chem Biol. 2020 Feb;16(2):111-112. doi: 10.1038/s41589-019-0448-6. Nat Chem Biol. 2020. PMID: 31932722 No abstract available.
Protocol for performing pooled CRISPR-Cas9 loss-of-function screens.
Mathiowetz AJ, Roberts MA, Morgens DW, Olzmann JA, Li Z. Mathiowetz AJ, et al. Among authors: li z. STAR Protoc. 2023 Mar 30;4(2):102201. doi: 10.1016/j.xpro.2023.102201. Online ahead of print. STAR Protoc. 2023. PMID: 37000620 Free PMC article.
Lipid Quality Control and Ferroptosis: From Concept to Mechanism.
Li Z, Lange M, Dixon SJ, Olzmann JA. Li Z, et al. Annu Rev Biochem. 2023 Nov 14:10.1146/annurev-biochem-052521-033527. doi: 10.1146/annurev-biochem-052521-033527. Online ahead of print. Annu Rev Biochem. 2023. PMID: 37963395 Review.
103,626 results
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